Results 221 to 230 of about 51,375 (298)

Speculation in the United Kingdom, 1785‒2019

open access: yesThe Economic History Review, EarlyView.
Abstract Speculation has long been thought to have significant economic effects, but it is difficult to measure, making it challenging to examine these effects empirically. In this paper we measure speculation in the United Kingdom since 1785 by using business and financial reporting in The Times newspaper.
William Quinn   +2 more
wiley   +1 more source

Adults' leisure-time physical activity preferences and association with physical activity guidelines by metropolitan status, United States, 2019. [PDF]

open access: yesPLoS One
Abildso CG   +10 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation

open access: yesThe FEBS Journal, EarlyView.
Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev   +2 more
wiley   +1 more source

Global health and climate benefits from walking and cycling infrastructure. [PDF]

open access: yesProc Natl Acad Sci U S A
Millard-Ball A   +3 more
europepmc   +1 more source

Rethinking informal circularity through metanarratives: Tensions, insights and directions for management research

open access: yesInternational Journal of Management Reviews, EarlyView.
Abstract This study explores the intersection of the informal and circular economies and its implications for business, management and organization (BMO) scholarship and practice. Informal circularity, practices of collecting, reusing, repairing, recycling and repurposing materials outside formal economic, legal and regulatory arrangements, constitutes
Tulin Dzhengiz   +3 more
wiley   +1 more source

A Conversation With David Bellhouse

open access: yesInternational Statistical Review, EarlyView.
Summary David Richard Bellhouse was born in Winnipeg, Manitoba, on 19 July 1948. He studied actuarial mathematics and statistics at the University of Manitoba (BA, 1970; MA, 1972) and completed his PhD at the University of Waterloo, Ontario, in 1975. After being an Assistant Professor for 1 year at his alma mater, he joined the University of Western ...
Christian Genest
wiley   +1 more source

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