Results 71 to 80 of about 11,786 (256)

Cerebellar Abnormalities in the Neuroimaging Spectrum of CLTC‐Related Disorder

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in CLTC, which encodes the clathrin heavy chain involved in vesicle‐mediated trafficking in neurons, cause a rare neurodevelopmental disorder associated with variable severity of global developmental delay and intellectual disability and structural brain abnormalities. Although corpus callosum and white matter anomalies are
Daniel Charouf, Andrea Accogli, Fadi F. Hamdan, Francesca Nardecchia, Toshiyuki Itai, Kenneth A. Myers, Christine Saint Martin, Myriam Srour   +7 more
wiley   +1 more source

T‐Shaped Stibenium(III) Cation: Hydrostibination Without Sb─H Bond

Angewandte Chemie, EarlyView.
A cationic, structurally constrained stibenium platform mediates anti‐Markovnikov hydrostibination of alkenes via element–ligand cooperativity (ELC), thereby bypassing the need for weak Sb─H bonds. ABSTRACT The hydrostibination of alkenes represents a largely underdeveloped transformation, owing to the intrinsic lability of the required Sb─H reagents ...
Ekta Nag, Lars Ole Busse, Andreas Albers, Manuel Schmitt, Lutz Greb   +4 more
wiley   +2 more sources

Early Endoscopic Repair of Traumatic Skull Base Dural Injuries: Challenging the Dogma of Conservative Management

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Traditional management of traumatic skull base dural injury has often favored observation and conservative therapy, despite the risk of delayed intracranial complications. This paradigm originated when operative intervention required craniotomy and carried significant morbidity.
Jessica W. Grayson, Madeline P. Bald, Lauren McLeod, Adam J. Skelton, Nicolaus D. Knight, Do‐Yeon Cho, Justin Turner, Hari Jeyarajan, Kristen O. Riley, Bradford A. Woodworth   +9 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Design and Construction of a Virtual Bicycle Simulator for Evaluating Sustainable Facilities Design

Advances in Civil Engineering, 2018
The rising interest in sustainable modes of transportation has increased demand for the design and implementation of bicycle facilities in the United States. However, as compared to the vehicular mode, bicycle facilities have relatively less development,
Carlos Sun, Zhu Qing
doaj   +1 more source

Bismuth Bicycles

Journal of Peptide Science
ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules. Phage‐encoded libraries of bicyclic peptides enable the discovery of high‐affinity molecules against virtually any protein target.
Saan Voss, Amin Sagar, Arnaud Tiberghien, Richard J. L. Hughes, Liuhong Chen, Inmaculada Rioja, Mark Frigerio, Michael J. Skynner, David R. Spring   +8 more
openaire   +3 more sources

Active commuting of the inhabitants of Liberec city in low and high walkability areas

Acta Gymnica, 2015
Background: Active commuting in terms of everyday transport to school or work can have a significant effect on physical activity. Active commuting can be influenced by the environment, and examples from abroad show that current environmental changes tend
Lukáš Rubín, Josef Mitáš, Jan Dygrýn, Jiří Šmída, Lukáš Gábor, Adam Pátek   +5 more
doaj   +1 more source

Transport bicycles

Proceedings of the National Academy of Sciences, 1997
Uphill transport of one substrate (the driven substrate) can be coupled to the dissipation of an electrochemical potential gradient of another substrate (the driving substrate), to an exergonic chemical reaction, or to a photoreaction. In all cases, the driven substrate is taken up from a low concentration (or relatively low electrochemical potential ...
openaire   +3 more sources

Artificial Intelligence (AI) and Agribusiness: From Automation to Augmentation in a Global Context

Agribusiness, EarlyView.
Alexis H. Villacis
wiley   +1 more source

Detroit Bike City and the Reconstitution of Community

Open Philosophy, 2020
In recent years a burgeoning bicycle culture has reanimated the city of Detroit. The following essay analyzes this reanimation through the themes of embodiment, mobility, spatiality, and the intersubjective creation of place, using the techniques of ...
Koukal D. R.
doaj   +1 more source