Results 51 to 60 of about 17,376 (234)

Prevalence, Prevention and Treatment of Saddle Sores among Female Competitive Cyclists: A Scoping Review Protocol

open access: yesMethods and Protocols, 2020
Female cyclists are prone to a variety of injuries and illnesses that occur as a result of prolonged contact with a bicycle saddle. Saddle sores are a range of skin ailments on the buttocks, genitals and inner thigh that result from a combination of ...
Keira Bury   +3 more
doaj   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

open access: yesAdvanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei   +10 more
wiley   +1 more source

The Relationship between Functional Fitness and Ability to Ride a Bicycle among Community-Dwelling Older Adult in Japan

open access: yesPhysical Activity and Health, 2021
Background: Bicycling is a good mode of transportation for people of all ages. The ability to ride a bicycle requires sufficient physical abilities. This study aimed to examine the relationship between functional fitness and the ability to ride a bicycle
Ryuichi Hasegawa   +5 more
doaj   +1 more source

Isosorbide‐Based Optically Clear Adhesives With Ultrahigh Transparency and Rapid Strain Recovery for Flexible Displays

open access: yesAdvanced Science, EarlyView.
Biomass‐derived isosorbide‐based PUDA crosslinker enables optically clear adhesives with ultrahigh transparency (99.8%), rapid strain recovery, and stable adhesion for flexible displays. ABSTRACT Flexible and foldable displays require optically clear adhesives (OCAs) that combine ultrahigh optical transparency with mechanical resilience under repeated ...
Yoonji Choi   +8 more
wiley   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

open access: yesAngewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang   +1 more
wiley   +2 more sources

Estimating Bicycling Demand

open access: yes, 2005
Simple and reliable tools for estimating and predicting the amount of bicycling in an area would be useful for a variety of investment and policy decisions.
Kevin Krizek, Gary Barnes
core   +1 more source

Health Impacts of Urban Bicycling in Mexico

open access: yes, 2021
Background: Bicycling has been associated with health benefits. Local and national authorities have been promoting bicycling as a tool to improve public health and the environment.
David Rojas-Rueda
core   +1 more source

The importance of individual characteristics on bicycle performance during alcohol intoxication

open access: yesTraffic Safety Research
Bicycling accidents are a well-known problem for traffic safety globally. Alcohol intoxication is one possible factor, although the exact number of accidents due to intoxication is difficult to establish.
Caroline Andersérs   +2 more
doaj   +1 more source

Can You Ride a Bicycle? The Ability to Ride a Bicycle Prevents Reduced Social Function in Older Adults With Mobility Limitation

open access: yesJournal of Epidemiology, 2016
Background: The health benefits of bicycling in older adults with mobility limitation (ML) are unclear. We investigated ML and functional capacity of older cyclists by evaluating their instrumental activities of daily living (IADL), intellectual activity,
Ryota Sakura
doaj   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang   +11 more
wiley   +1 more source

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