Results 51 to 60 of about 15,640 (302)
Advanced Science, EarlyView.TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin +11 more
wiley +1 more source
Angewandte Chemie, EarlyView.The excited‐state antiaromaticity of hydroxybenzotropyliums (HBTs) can be tuned through substituent effects to bring the aromatic ‘enol’ (E) and keto (K) tautomers close in energy. This leads to abnormally slow excited‐state proton transfer (on the ns timescale), giving rise to dual fluorescence emission and weak photoacidity.
Promeet K. Saha +6 more
wiley +2 more sources
Strengthening Active Transportation Through Small Grants
Future TransportationBicycle use has been increasing in many countries for active, sustainable transportation and recreation. Bicycling can benefit an individual’s mental and physical health and contribute to a community’s well-being and desirability, and it is more ...
Charles Chancellor +4 more
doaj +1 more source
Brain and Behavior, 2021 Background Efficacy of exercise to improve motor symptoms in Parkinson's Disease (PD) has been established in multiple clinical trials. The Pedaling for Parkinson's ™ (PFP) program is an existing community‐based cycling intervention for individuals with ...
Kathleen E. McKee +3 more
doaj +1 more source
, 2005 Simple and reliable tools for estimating and predicting the amount of bicycling in an area would be useful for a variety of investment and policy decisions.
Kevin Krizek, Gary Barnes
core +1 more source
An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring
Advanced Science, EarlyView.This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.Three‐component thio‐ and carbo‐boration reactions to form functionalised benzoxaborinines and benzazaborinines are reported. The nucleophile scope includes thioethers, thiols, and (hetero)arenes. Mechanistic studies revealed a disparity between thioboration using thioethers and using thiols.
Laura Winfrey +4 more
wiley +2 more sources
Do Online Bicycle Routing Portals Adequately Address Prevalent Safety Concerns?
Safety, 2018 Safety concerns are among the most prevalent deterrents for bicycling. The provision of adequate bicycling infrastructure is considered as one of the most efficient means to increase cycling safety.
Martin Loidl, Hartwig H. Hochmair
doaj +1 more source
FOSTERING BICYCLING CULTURE IN THE INSTITUTIONAL POLICY PLANNING OF CITIES
Journal of Physical Education, 2021 The objective this research understand perspective of cycloactivists South Region of Brazil in the promotion biciculture in their respective territories.
Leandro Dri Manfiolete Troncoso +4 more
doaj +1 more source
International Mountain Bicycling Association (IMBA) 1999 Advocacy Survey Summary [PDF]
, 1999 In May 1999 the International Mountain Bicycling Association (IMBA) conducted a postcard advocacy survey of members and non-member mountain bikers. The survey focused on overall impressions about trail access, IMBA's role in keeping trails open and the ...
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