Results 71 to 80 of about 3,237,044 (306)

Dynamic bidding strategies in search-based advertising [PDF]

open access: yesAnnals of Operations Research, 2013
Search-based advertising allows the advertisers to run special campaigns targeted to different groups of potential consumers at low costs. Google, Yahoo and Microsoft advertising programs allow the advertisers to bid for an ad position on the result page of a user’s query when the user searches for a keyword that the advertiser relates to its products ...
Dayanik, S., Parlar, M.
openaire   +5 more sources

Heuristic bidding strategies for multiple heterogeneous auctions

open access: yes, 2006
This paper investigates utility maximising bidding heuristics for agents that participate in multiple heterogeneous auctions, in which the auction format and the starting and closing times can be different.
Byde, A   +8 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A heuristic bidding strategy for multiple heterogeneous auctions

open access: yes, 2003
Online auctions are increasingly being used as a medium to procure goods and services. As the number of auction sites increases, however, consumers will inevitably want to track and bid in multiple auctions (with multiple protocols) in order to get the ...
Jennings, N. R., Anthony, P.
core   +2 more sources

An Empirical Study of Contractors’ Bidding Trends in Recurrent Bidding: A Case of Singapore Public Sector Construction Projects

open access: yesBuildings
There have been limited empirical studies that aimed to establish the tenability of the stationarity assumption in recurrent construction bidding, and thus the need for and importance of allowing for continuity in bidding models remain unexplored.
Yixi Zhang   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Day-Ahead Two-Stage Bidding Strategy for Multi-Photovoltaic Storage Charging Stations Based on Bidding Space

open access: yesWorld Electric Vehicle Journal
Against the backdrop of a “dual-carbon” strategy, the use of photovoltaic storage charging stations (PSCSs), as an effective way to aggregate and manage electric vehicles, new energy sources, and energy storage, will be an important primary component of ...
Fulu Yan   +3 more
doaj   +1 more source

Electric power bidding model for practical utility system

open access: yesAlexandria Engineering Journal, 2018
A competitive open market environment has been created due to the restructuring in the electricity market. In the new competitive market, mostly a centrally operated pool with a power exchange has been introduced to meet the offers from the competing ...
M. Prabavathi, R. Gnanadass
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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