Results 151 to 160 of about 26,143 (304)

Salt Stress Induces Imbalanced ADI Pathway Gene Expressions in Pediococcus acidilactici Drives Citrulline Accumulation as an Ethyl Carbamate Precursor in Soy Sauce

open access: yesFood Bioengineering, EarlyView.
ABSTRACT Citrulline is the main precursor of a carcinogen compound ethyl carbamate (EC) in soy sauce. Accumulation of citrulline is mainly related to metabolism of arginine by Pediococcus acidilactici via the arginine deiminase (ADI) pathway during soy sauce fermentation.
Xiaodie Chen   +3 more
wiley   +1 more source

A Deep Learning Framework for Forecasting Medium‐Term Covariance in Multiasset Portfolios

open access: yesJournal of Forecasting, EarlyView.
ABSTRACT Forecasting the covariance matrix of asset returns is central to portfolio construction, risk management, and asset pricing. However, most existing models struggle at medium‐term horizons, several weeks to months, where shifting market regimes and slower dynamics prevail.
Pedro Reis, Ana Paula Serra, João Gama
wiley   +1 more source

Design And Development Of Boost A Converter Using Planar Inductor For Dual Supply Automotive System [PDF]

open access: yes, 2008
Today, innovation in electronic automobile components has resulted in the need for higher voltage power supplies. In future automotive vehicles will have 36V operating system.
Krishnan, Shashikumar
core  

Gradual volatile memristor–based artificial neurons with high uniformity for neuromorphic computing

open access: yesInfoScience, EarlyView.
Schematic of leaky integrate‐and‐fire artificial neurons for MNIST image classification. Abstract Artificial neurons are pivotal for neuromorphic hardware, but the development of compact and uniform devices remains challenging. Conventional volatile memristors suffer from abrupt switching, which hinders spatiotemporal consistency.
Pengtao Li   +12 more
wiley   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

Coupling Water Purification and Carbon Sequestration at Various Spatial Scales From Supply and Demand Perspective

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Balancing ecosystem‐service supply and demand is central to understanding both the natural and social dimensions of ecosystem services and to enhancing human well‐beings. Concurrently, collaborative efforts are underway to improve multiple ecosystem services, including the promotion of carbon neutrality and water purification (WP) within basin
Jing Cheng   +5 more
wiley   +1 more source

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang   +3 more
wiley   +1 more source

Frequency Domain Analysis of Dual Active Bridge DC-DC Converter with Series Resonant

open access: yesKongzhi Yu Xinxi Jishu, 2017
Isolated bidirectional DC/DC converter is the core of power electronic transformer and influences the performance and efficiency of the system. Switching losses can be reduced and bidirectional power flow can be easily achieved with the use of series ...
WANG Shien, ZHENG Zedong, LI Yongdong
doaj  

Inflammation, Immunity, and Cardiovascular Diseases

open access: yesMed Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo   +8 more
wiley   +1 more source

A Comprehensive Multistage Average Controller for Trajectory Tracking in Solar‐Powered Mobile Robots: Analysis of Actuator‐Driver and Power Stage Integration

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT This work addresses the challenge of bidirectional trajectory tracking in solar‐powered wheeled mobile robots (WMRs), considering the mechanical structure, actuator‐driver, and power stage subsystems. Notably, this is the first study to explicitly model and control the actuator‐driver subsystem within this context. The proposed solution relies
Benjamin Natanael Santiago‐Nogales   +8 more
wiley   +1 more source

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