Results 181 to 190 of about 931,300 (210)
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González +14 more
wiley +1 more source
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque +11 more
wiley +1 more source
Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko +2 more
wiley +1 more source
Flexible Tactile Actuator Arrays With Integrated Electroosmotic Pumps for Wearable Haptic Systems
1 ×$\times$ 9 and 4 ×$\times$ 4 flexible tactile actuator arrays integrating electroosmotic pumps are developed to deliver pressure and vibration feedback on wearable platforms. Their thin, compliant structure conforms seamlessly to curved body surfaces, providing intimate contact and enhanced haptic sensations.
Heejin Yu, Joonbum Bae
wiley +1 more source
This study presents a soft pneumatic fabric bidirectional actuation module (PNEUMA) capable of generating high torque in both bending directions within a single integrated architecture. PNEUMA achieves up to 50 Nm with reduced inflation volume and a lightweight design.
Odysseas Simatos +2 more
wiley +1 more source
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng +3 more
wiley +1 more source
This paper reviews recent advances in hybrid deep learning for intelligent fault diagnosis of rotating machinery, focusing on GAN‐ and CNN‐based architectures and their specialized variants. Hybrid GAN‐CNN methods are categorized into three groups: (1) optimized original GANs with CNN variants, (2) improved GAN architectures integrated with CNNs, and ...
Temesgen Tadesse Feisa +7 more
wiley +1 more source
Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah +5 more
wiley +1 more source
Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo +8 more
wiley +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source

