Results 121 to 130 of about 5,951 (240)

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

open access: yesInterdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang   +22 more
wiley   +1 more source

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

open access: yesThe Journal of Pathology, EarlyView.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup   +12 more
wiley   +1 more source

A Review of Mechanical Reinforcement and Piezoresistive Self‐Sensing in Carbon Nanotube Fiber Composites

open access: yesPolymer Composites, EarlyView.
PSPP‐TRL mapping of CNT‐modified CFRP literature, with four recurring confusions resolved and five scale‐up problems quantified. ABSTRACT Carbon nanotube‐modified fiber composites are often presented as a route to stronger, tougher, and self‐sensing structural materials.
Sanan H. Khan
wiley   +1 more source

Brain‐Inspired Neuromorphic Device for Artificial Intelligent Robots Applications

open access: yesSmartBot, EarlyView.
Brain‐inspired neuromorphic devices mimic biological systems to provide an efficient hardware foundation for embodied intelligent robotics. This review explores the material systems and corresponding computing architectures of neuromorphic devices that support low‐power perception, adaptive learning, and real‐time decision‐making.
Jiachen Han   +3 more
wiley   +1 more source

Exploiting Device Deformability for Fluid and Particle Manipulation

open access: yesSmall, EarlyView.
Deformable devices enable fluid and particle manipulation modes that are inaccessible to rigid platforms. This review examines soft materials and architectures that translate controlled deformation into microscale fluid operations such as pumping, valving, mixing, and particle handling.
Zhiyang Hong   +4 more
wiley   +1 more source

Attention Pooling-Based Bidirectional Gated Recurrent Units Model for Sentimental Classification

open access: yesInternational Journal of Computational Intelligence Systems, 2019
Dejun Zhang   +6 more
openaire   +1 more source

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