Clinical Safety and Tolerability of <i>Bifidobacterium bifidum</i> BBi32: An 8-Week Randomized, Double-Blind, Placebo-Controlled Trial With Genomic and In Vitro Corroboration. [PDF]
An 8‐week randomized, double‐blind, placebo‐controlled trial found BBi32 well tolerated with no hematologic or hepatic abnormalities. Versus placebo, BBi32 reduced uric acid/urea/creatinine, increased LL‐37, and lowered gastrointestinal symptom scores.
Fang S +5 more
europepmc +2 more sources
In Silico Assigned Resistance Genes Confer Bifidobacterium with Partial Resistance to Aminoglycosides but Not to Β-Lactams [PDF]
peer-reviewedBifidobacteria have received significant attention due to their contribution to human gut health and the use of specific strains as probiotics.
Cotter, Paul D. +6 more
core +13 more sources
Effects of synbiotic supplement on human gut microbiota, body composition and weight loss in obesity [PDF]
Targeting gut microbiota with synbiotics (probiotic supplements containing prebiotic components) is emerging as a promising intervention in the comprehensive nutritional approach to reducing obesity.
Aljutaily, T. +3 more
core +1 more source
In vitro screening of probiotic lactic acid bacteria and prebiotic glucooligosaccharides to select effective synbiotics [PDF]
Probiotics and prebiotics have been demonstrated to positively modulate the intestinal microflora and could promote host health. Although some studies have been performed on combinations of probiotics and prebiotics, constituting synbiotics, results on ...
Courtin, Céline +6 more
core +2 more sources
Bifidobacteria and lactobacilli in the gut microbiome of children with non-alcoholic fatty liver disease: which strains act as health players? [PDF]
Introduction: Non-alcoholic fatty liver disease (NAFLD), considered the leading cause of chronic liver disease in children, can often progress from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).
Alisi, A +9 more
core +3 more sources
Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria. [PDF]
Breast milk enhances the predominance of Bifidobacterium species in the infant gut, probably due to its large concentration of human milk oligosaccharides (HMO). Here we screened infant-gut isolates of Bifidobacterium longum subsp.
Garrido, Daniel +5 more
core +2 more sources
Growth of bifidobacteria in mammalian milk [PDF]
Microbial colonization of the mammalian intestine begins at birth, when from a sterile state a newborn infant is exposed to an external environment rich in various bacterial species.
Bunešová, V. +7 more
core +1 more source
Role of Bifidobacterium bifidum and plant food extracts in improving microflora and biochemical and cytogenetic parameters in adjuvant arthritis. [PDF]
The aim of the present research was to discover plant food extracts and probiotics that may have bioactivity towards chronic inflammation. Three plant food extract mixtures expected to be rich in phenolic compounds, carotenoids and tocopherols were ...
Abd El Khalek, A. B. +3 more
core +3 more sources
Occurrence and diversity of CRISPR-Cas systems in the genus bifidobacterium [PDF]
CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas ...
Barrangou, Rodolphe +3 more
core +1 more source
Bifidobacterium breve UCC2003 metabolises the human milk oligosaccharides lacto-N-tetraose and lacto-N-neo-tetraose through overlapping, yet distinct pathways [PDF]
In this study, we demonstrate that the prototype B. breve strain UCC2003 possesses specific metabolic pathways for the utilisation of lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT), which represent the central moieties of Type I and Type II human ...
Bottacini, Francesca +3 more
core +2 more sources

