Results 211 to 220 of about 47,587 (228)

Bifidobacterium bifidum E3 Combined with Bifidobacterium longum subsp. infantis E4 Improves LPS-Induced Intestinal Injury by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways In Vivo.

Journal of Agricultural and Food Chemistry, 2023
Changes in the functions of the intestinal barrier occur in parallel with the development of sepsis. The protection by Bifidobacterium strains (BB, BL, BB12, and BLBB) was evaluated in mice injected with lipopolysaccharide (LPS).
Yingxue Yue, Yuqi Wang, Qinggang Xie, Xiuli Lv, Linyi Zhou, Etareri Evivie Smith, Ting Cao, Yifan Zhang, Bailiang Li, G. Huo, Weiwei Ma   +10 more
semanticscholar   +1 more source

Establishment of a gut-on-a-chip device with controllable oxygen gradients to study the contribution of Bifidobacterium bifidum to inflammatory bowel disease.

Biomaterials Science, 2023
Supplemental Bifidobacterium has been shown to aid in the prevention, alleviation, and treatment of inflammatory bowel disease (IBD), but the progression and mechanisms are largely unstudied, partly because of a lack of appropriate models. In vitro human
Jun Liu, R.C.C. Lu, Xiaolin Zheng, W. Hou, Xiaoying Wu, Hezhao Zhao, Guixue Wang, Tian Tian   +7 more
semanticscholar   +1 more source

Bifidobacterium bifidum FJSWX19M5 alleviated 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced chronic colitis by mitigating gut barrier injury and increasing regulatory T cells.

Food & Function, 2023
Probiotics have been evaluated as alternative approaches for preventing the relapse of Crohn's disease (CD). Previously, we observed strain-specific anti-inflammatory properties of Bifidobacterium bifidum in 2,4,6-trinitrobenzene sulfonic acid (TNBS ...
DingWu Qu, Leilei Yu, F. Tian, Hao Zhang, Wei Chen, Zhennan Gu, Q. Zhai   +6 more
semanticscholar   +1 more source

Bifidobacterium bifidum BGN4 fractions ameliorate palmitic acid-induced hepatocyte ferroptosis by inhibiting SREBP1-CYP2E1 pathway

Journal of Investigative Medicine, 2023
Metabolic dysfunction-associated fatty liver disease (MAFLD) is strongly associated with disturbances in the intestinal microbiota. Herein, the biological effects and mechanism of Bifidobacterium bifidum BGN4 fractions in regulating hepatocyte ...
G. Bu, Gang Chen, Juan Li, Dan Wu, Jia-Qi Liao   +4 more
semanticscholar   +1 more source

A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of the gut microbiota and relief from chronic constipation.

Food & Function, 2022
A variety of opinions exist on the potential of probiotics to provide relief from chronic constipation with much focus being placed on their mechanism of action and causes of heterogeneity in the results of different studies.
Luyao Wang, Linlin Wang, Peijun Tian, Botao Wang, Shumao Cui, Jianxin Zhao, Hao Zhang, Long Qian, Qun Wang, Wei Chen, G. Wang   +10 more
semanticscholar   +1 more source

Bifidobacterium bifidum relieved DSS-induced colitis in mice potentially by activating the aryl hydrocarbon receptor.

Food & Function, 2022
Inflammatory bowel disease (IBD) characterized by relapsed intestinal inflammation and barrier function disruption is still a great therapeutic challenge.
Qingyu Cui, Xiaoying Tian, Xi Liang, Zhe Zhang, Rui Wang, Yu Zhou, H. Yi, P. Gong, Kai Lin, Tongjie Liu, Lanwei Zhang   +10 more
semanticscholar   +1 more source

Bifidobacterium bifidum H3-R2 and Its Molecular Communication within the Context of Ulcerative Colitis.

Journal of Agricultural and Food Chemistry, 2022
Bifidobacteria are important mediators of immune system development within the gastrointestinal system and immunological homeostasis. The present study explored the anti-colitic activity of Bifidobacterium bifidum H3-R2 in a murine dextran sulfate sodium
Jiacui Shang, Shuo Yang, Zongxin Tang, Yuhan Chen, Bofan Duan, Xiangchen Meng   +5 more
semanticscholar   +1 more source

Bifidobacterium bifidum BGN4 Paraprobiotic Supplementation Alleviates Experimental Colitis by Maintaining Gut Barrier and Suppressing Nuclear Factor Kappa B Activation Signaling Molecules.

Journal of Medicinal Food, 2022
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are characterized by chronic gastrointestinal inflammation with continuous relapse-remission cycles.
So-Young Lee, Byung-Hoo Lee, Jong-Hyun Park, Myeong-Soo Park, G. Ji, Mi-Kyung Sung   +5 more
semanticscholar   +1 more source

O-acetylesterase activity of Bifidobacterium bifidum sialidase facilities the liberation of sialic acid and encourages the proliferation of sialic acid scavenging Bifidobacterium breve.

Environmental Microbiology Reports, 2022
Bifidobacterium bifidum possesses two extracellular sialidases (SiaBb1 and SiaBb2) that release free sialic acid from mucin sialoglycans, which can be utilized via cross-feeding by Bifidobacterium breve that, otherwise, is prevented from utilizing this ...
Tatsunari Yokoi, Keita Nishiyama, Yuka Kushida, Kazuya Uribayashi, Takahiro Kunihara, Rikako Fujimoto, Yuji Yamamoto, Masahiro Ito, T. Miki, Takeshi Haneda, T. Mukai, N. Okada   +11 more
semanticscholar   +1 more source

Bifidobacterium bifidum Ameliorates DSS-Induced Colitis in Mice by Regulating Microbial Metabolome and Targeting Gut Microbiota.

Journal of Agricultural and Food Chemistry
Inflammatory bowel disease (IBD) is a recurrent inflammatory condition affecting the gastrointestinal tract, and its clinical treatment remains suboptimal.
Mengzhen Han, Jingjing Liang, Mengxin Hou, Yuanye Liu, Hongcai Li, Zhenpeng Gao   +5 more
semanticscholar   +1 more source