Evolution of substrate specificity in a retained enzyme driven by gene loss. [PDF]
The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that ...
Babnigg, Gyorgy +14 more
core +1 more source
Defective intestinal tight junction (TJ) barrier is a hallmark in the pathogenesis of inflammatory bowel disease (IBD). To date, there are no effective therapies that specifically target the intestinal TJ barrier.
Rana Al-Sadi +6 more
semanticscholar +1 more source
Bifidobacterium breve UCC2003 metabolises the human milk oligosaccharides lacto-N-tetraose and lacto-N-neo-tetraose through overlapping, yet distinct pathways [PDF]
In this study, we demonstrate that the prototype B. breve strain UCC2003 possesses specific metabolic pathways for the utilisation of lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT), which represent the central moieties of Type I and Type II human ...
Bottacini, Francesca +3 more
core +2 more sources
Paraprobiotics, inactivated microbial cells, regulate immune system and exhibit antioxidant and anti-inflammatory activities in patients with weakened immunity or the elderly. This study evaluated the anti-tumor effects of heat-killed Bifidobacterium and
SukJin Kim +5 more
semanticscholar +1 more source
Occurrence and diversity of CRISPR-Cas systems in the genus bifidobacterium [PDF]
CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas ...
Barrangou, Rodolphe +3 more
core +1 more source
The paper presents a study on bactericidal properties of Bifidobacterium bifidum exometabolites in respect of antibiotic-resistant hospital isolates: Staphylococcus aureus 889 (MRSA), Staphylococcus epidermidis 2041, Pseudomonasaeruginosa 2853, obtained ...
A. A. Markov +3 more
doaj
Bifidobacteria and their role as members of the human gut microbiota [PDF]
Members of the genus Bifidobacterium are among the first microbes to colonize the human gastrointestinal tract and are believed to exert positive health benefits on their host.
O'Callaghan, Amy, van Sinderen, Douwe
core +1 more source
Encapsulation of Bifidobacterium longum in alginate-dairy matrices and survival in simulated gastrointestinal conditions, refrigeration, cow milk and goat milk [PDF]
The aim of this study was to microencapsulate Bifidobacterium longum subsp. infantis CCUG 52486 using the extrusion method in a variety of matrices, namely sodium alginate (SA), sodium alginate-cow milk (SACM), sodium alginate-goat milk (SAGM) and sodium
Charalampopoulos, D., Prasanna, P. H. P.
core +1 more source
Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut [PDF]
Bifidobacteria are common and frequently dominant members of the gut microbiota of many animals, including mammals and insects. Carbohydrates are considered key carbon sources for the gut microbiota, imposing strong selective pressure on the complex ...
Hevia, Arancha +4 more
core +1 more source
Comparative composition, diversity, and abundance of oligosaccharides in early lactation milk from commercial dairy and beef cows. [PDF]
Prebiotics are nondigestible dietary ingredients, usually oligosaccharides (OS), that provide a health benefit to the host by directly modulating the gut microbiota.
Barile, Daniela +4 more
core +2 more sources

