????????? ??????????????? ?????? ??????????????? ?????? ??????????????? [PDF]
Department of Energy Engineering (Battery Science and Technology)The continuous throng in demand for high energy density rechargeable batteries innovatively drives technological development in cell design as well as electrochemically active materials. In
Jeong, Dae-Hyeon
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Oligomerization Route to Py-Im Polyamide Macrocycles [PDF]
Cyclic eight-ring pyrrole−imidazole polyamides are sequence-specific DNA-binding small molecules that are cell permeable and can regulate endogenous gene expression.
Chenoweth, David M. +2 more
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A review of developments in electrodes for regenerative polymer electrolyte fuel cells [PDF]
The design of electrodes for unitised regenerative polymer electrolyte fuel cells (URFC) requires a delicate balancing of transport media. Gas transport, electrons and protons must be carefully optimised to provide efficient transport to and from the ...
Harrison, DJ, Pettersson, J, Ramsey, BJ
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An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma [PDF]
The conserved Myb-MuvB (MMB) multiprotein complex has an important role in transcriptional activation of mitotic genes. MMB target genes are overexpressed in several different cancer types and their elevated expression is associated with an advanced ...
Francke, S. +10 more
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The aminoindanol core as a key scaffold in bifunctional organocatalysts
The 1,2-aminoindanol scaffold has been found to be very efficient, enhancing the enantioselectivity when present in organocatalysts. This may be explained by its ability to induce a bifunctional activation of the substrates involved in the reaction. Thus,
Isaac G. Sonsona +2 more
doaj +1 more source
Dynamic Kinetic Resolution of Hetero biaryl Ketones by Zinc- Catalyzed Asymmetr ic Hydrosil ylation [PDF]
Adiastereo- and highly enantioselective dynamic kinetic resolution (DKR) of configurationally labile hetero- biaryl ketones is described. The DKR proceeds by zinc- catalyze dhydrosilylation of the carbonyl group ,thus leading to ...
Carmona, José A. +6 more
core +1 more source
A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase [PDF]
Simocyclinones are bifunctional antibiotics that inhibit bacterial DNA gyrase by preventing DNA binding to the enzyme. We report the crystal structure of the complex formed between the N-terminal domain of the Escherichia coli gyrase A subunit and ...
A. Maxwell +29 more
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In this work, mesoporous silica materials SBA-15 functionalized with propyl/ phenyl-sulfonic acid group were synthesized and loaded with Pt to form bifunctional catalysts.
Liuye Mo +4 more
doaj +1 more source
Novel Molecules for Intra-Oral Delivery of Antimicrobials to Prevent and Treat Oral Infectious Diseases [PDF]
New molecules were designed for efficient intra-oral delivery of antimicrobials to prevent and treat oral infection. The salivary statherin fragment, which has high affinity for the tooth enamel, was used as a carrier peptide. This was linked through the
Dentino, Andrew R. +2 more
core +1 more source
Acylsulfonamide safety-catch linker : promise and limitations for solid-phase oligosaccharide synthesis [PDF]
Safety-catch linkers are useful for solid-phase oligosaccharide synthesis as they are orthogonal to many common protective groups. A new acylsulfonamide safety-catch linker was designed, synthesized and employed during glycosylations using an automated ...
Collot, M. +3 more
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