Results 171 to 180 of about 206,176 (338)
Advanced Science, EarlyView.Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao +8 more
wiley +1 more source
Synergism, Bifunctionality, and the Evolution of a Gradual Sensory Trade-off in Hummingbird Taste Receptors [PDF]
, 2021 Glenn Cockburn +9 more
openalex +1 more source
Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation
Advanced Science, EarlyView.Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong +13 more
wiley +1 more source
Bifunctional Catalysts with Separated and Tunable Sites on Zeolites for Relay Catalysis of the Oxidative Dehydrogenation of Propane Using CO2 [PDF]
Wanting Li +9 more
openalex +1 more source
Advanced Science, EarlyView.Valence‐engineering of CeO2 redox modulator can remove the highly oxidative by‐products and accelerate the oxidation state transitions of Co/Fe centers in FeCo dual‐atom catalyst during oxygen reduction/evolution electrocatalysis. Therefore, the stability and activity issues are resolved, significantly enhancing the overall performance when used as an ...
Hengqi Liu +10 more
wiley +1 more source