Results 91 to 100 of about 104,054 (264)

Quasi-Periodic Bifurcations and Chaos

Mathematics
A natural phenomenon in applications is the interaction of quasi-periodic solutions of dynamical systems in a dissipative setting. We study the interactions of two of such ODE systems based on the construction of a nonlinear oscillator with thermostatic (
Taoufik Bakri, Ferdinand Verhulst
doaj   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Periodic or homoclinic orbit bifurcated from a heteroclinic loop for high-dimensional systems

Open Mathematics
Consider an autonomous ordinary differential equation in Rn{{\mathbb{R}}}^{n}, which has a heteroclinic loop. Assume that the heteroclinic loop consists of two degenerate heteroclinic orbits γ1{\gamma }_{1}, γ2{\gamma }_{2} and two saddle points with ...
Long Bin, Yang Yiying
doaj   +1 more source

A Conservative Four-Dimensional Hyperchaotic Model with a Center Manifold and Infinitely Many Equilibria

Modelling
This paper presents a novel four-dimensional autonomous conservative model characterized by an infinite set of equilibrium points and an unusual algebraic structure in which all eigenvalues of the Jacobian matrix are zero.
Surma H. Ibrahim, Ali A. Shukur, Rizgar H. Salih   +2 more
doaj   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Effects of AC induced electric fields on neuronal firing sensitivity and activity patterns

Frontiers in Computational Neuroscience
IntroductionUnderstanding how neurons respond to time-varying electric fields is essential for both basic neuroscience and the development of neuromodulation strategies. However, the mechanisms by which alternating-current induced electric fields (AC-IEF)
Chunhua Yuan, Rupei Chen, Xiangyu Li, Yueyang Zhao   +3 more
doaj   +1 more source

Report of a Variation of the Right Common Carotid Artery [PDF]

Journal of Kerman University of Medical Sciences, 2018
Carotid artery is the most important artery that carries the major part of the blood supply to the head and neck. The branching of the common carotid artery usually occurs at the upper edge of the thyroid cartilage.
shabnam mohammadi, Nasibeh Ghandy
doaj  

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Exploring dynamical features like bifurcation assessment, sensitivity visualization, and solitary wave solutions of the integrable Akbota equation

Nonlinear Engineering
The Akbota equation (AE), as a Heisenberg ferromagnetic-type equation, can be extremely valuable in the study of curve and surface geometry. In this study, we employ the well-known two analytical techniques, the modified Khater method and the new sub ...
Chou Dean, Sagher Azad Ali, Asjad Muhammad Imran, Hamed Yasser Salah   +3 more
doaj   +1 more source