Results 131 to 140 of about 306,986 (339)
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu+7 more
wiley +1 more source
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu+18 more
wiley +1 more source
A new method for obtaining eigenvalues of variational inequalities based on bifurcation theory [PDF]
Milan Kučera
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Aminoferrocene is employed to modify black phosphorus, generating stable phosphorus radicals (FcP). The FcP is then functionalized with hyaluronic acid (HA) to produce the HA‐FcP radical complex, thereby developing a novel, highly efficient, sensitive, long‐lasting, and low‐heavy‐metal‐content radical contrast agent for targeted imaging of ...
Xiao Huang+6 more
wiley +1 more source
The bifurcation of periodic solutions in the Hodgkin-Huxley equations [PDF]
William C. Troy
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Dynamic Bonds Reinforced Polyamide Elastomer for Biomedical Orthosis
A dynamic bonds (DBs) reinforced shape memory polyamide elastomer is developed using reactive extrusion. Dynamic covalent networks enhance interlayer adhesion in 4D‐printed objects by utilizing the combined effects of multiple DBs, reducing mechanical anisotropy and improving the mechanical and shape memory properties.
Zhen Li+12 more
wiley +1 more source