Results 151 to 160 of about 23,444,297 (308)

Bistability and boundary crisis in a semiconductor laser with phase-conjugate feedback [PDF]

open access: yes, 2002
We present a detailed study of a route to chaos via quasiperiodicity on a torus in a semiconductor laser with phase-conjugate feedback. Highlighting the use of new tools that go far beyond mere simulation, we compute bifurcation diagrams and unstable ...
Green, K   +2 more
core  

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

open access: yesAdvanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan   +10 more
wiley   +1 more source

Computational Bifurcation Analysis

open access: yes
Bifurcation analysis collects techniques for characterizing the dependence of certain classes of solutions of a dynamical system on variations in problem parameters. Common solution classes of interest include equilibria and periodic orbits, the number and stability of which may vary as parameters vary.
Dankowicz, Harry, Sieber, Jan
openaire   +2 more sources

Spatiotemporally Precise Rheumatoid Arthritis Therapy via a Triple‐Locked Cascaded Nanoplatform With Dual‐Channel Self‐Reporting

open access: yesAdvanced Science, EarlyView.
An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu   +11 more
wiley   +1 more source

Dataset of "Analysis of a Hopf Bifurcation in a Neural System by Impedance Spectroscopy"

open access: yes
This dataset contains the raw data supporting the article "Analysis of a Hopf Bifurcation in a Neural System by Impedance Spectroscopy".The data were generated using custom Python scripts for solving and analyzing a neural oscillator model undergoing a ...
Bisquert, Juan   +1 more
core   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Bifurcations Analysis for Beginners

open access: yes
We study a class of hybrid dynamical systems that arise from various fields of mathematical sciences. We provide a rigorous analytical framework for the con- struction of the model, including explicit solutions within orthants, analytical determination of switching times, and the derivation of a boundary-to-boundary return map governing the global ...
openaire   +1 more source

An Integrated Framework Coupling Hierarchical Hyperspectral i‐trait Screening, Gene Identification, and Functional Validation for Genetic Dissection of Salt Tolerance in Cotton

open access: yesAdvanced Science, EarlyView.
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu   +11 more
wiley   +1 more source

A Bi‐Adjuvant Senolytic Nanovaccine Modulating Dendritic Cell Senescence Ameliorates Aging‐Related Metabolic Dysfunction

open access: yesAdvanced Science, EarlyView.
An active biomaterial‐based bi‐adjuvant nanovaccine restores the immunocompetence of aged dendritic cells to overcome senescent cell tolerance. Accompanied by the downregulation of mitotic kinases Aurka/b and attenuation of senescence‐associated PI3K/AKT phosphorylation, the nanovaccine enhances antigen‐presenting capacity and promotes potent cytotoxic
Qingxu Song   +5 more
wiley   +1 more source

CKMT1 Counteracts VDAC1 Oligomerization‐Induced Neuronal Pyroptosis Through Steric Hindrance in Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
CKMT1 inhibits VDAC1 oligomerization via a dual‐region mechanism: its NTD interacts with the VDAC1 C‐terminal domain, while residues 1–39 sterically hinder dimerization, thereby reducing mtDNA leakage and AIM2 inflammasome activation, suppressing neuronal pyroptosis and protecting against cerebral ischemic injury. ABSTRACT Ischemic stroke is one of the
Xiaoyu Wang   +17 more
wiley   +1 more source

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