Results 111 to 120 of about 173,676 (290)

Direction and Stability of Hopf Bifurcation in a Delayed Solow Model with Labor Demand

International Journal of Differential Equations, 2019
This paper is concerned with a delayed model of mutual interactions between the economically active population and the economic growth. The main purpose is to investigate the direction and stability of the bifurcating branch resulting from the increase ...
Sanaa ElFadily, Abdelilah Kaddar, Khalid Najib   +2 more
doaj   +1 more source

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

Advanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou, Mengxuan Bian, Lingyu Wei, Binghuang Yao, Qi Chen, Lan Xiao, Jing He, Jian Zhang, Yulin Li, Libo Jiang   +9 more
wiley   +1 more source

Intervals of bifurcation points for semilinear elliptic problems

Advances in Nonlinear Analysis
In this article, we study the behavior of multiple continua of solutions to the semilinear elliptic problem −Δu=λf(u),inΩ,u=0,on∂Ω,\left\{\begin{array}{ll}-\Delta u=\lambda f\left(u),\hspace{1.0em}& \hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em ...
Tapia José Carmona, Aparicio Antonio J. Martínez, Martínez-Aparicio Pedro J.   +2 more
doaj   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source

Bifurcation of solutions from infinity for certain nonlinear eigenvalue problems of fourth-order ordinary differential equations

Electronic Journal of Differential Equations, 2018
In this article, we study the global bifurcation from infinity of nonlinear eigenvalue problems for ordinary differential equations of fourth order. We prove the existence of unbounded continua of solutions emanating from asymptotically bifurcation ...
Ziyatkhan S. Aliyev, Natavan A. Mustafayeva   +1 more
doaj  

Research on Stability and Bifurcation for Two-Dimensional Two-Parameter Squared Discrete Dynamical Systems

Mathematics
This study investigates a class of two-dimensional, two-parameter squared discrete dynamical systems. It determines the conditions for local stability at the fixed points for these proposed systems.
Limei Liu, Xitong Zhong
doaj   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Hopf Bifurcation Analysis of the Halvorsen System

Zanco Journal of Pure and Applied Sciences
This paper investigates local bifurcations in the Halvorsen system, focusing specifically on transcritical and Hopf bifurcations. The behavior of equilibrium points during bifurcations is studied using Sotomayor's theorem for transcritical bifurcation ...
Kardo Baiz Othman, Adnan Ali Jalal
doaj   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source