Results 91 to 100 of about 25,747,115 (388)
Scientific ReportsConstruction industries remain one of the most significant users of materials and generators of waste in the UK and globally. Notwithstanding, the principle of circular economy is becoming prominent as an effective means for powering greater resource ...
Habeeb Balogun +7 more
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Analysis of Dimensionality Reduction Techniques on Big Data
IEEE Access, 2020 Due to digitization, a huge volume of data is being generated across several sectors such as healthcare, production, sales, IoT devices, Web, organizations. Machine learning algorithms are used to uncover patterns among the attributes of this data. Hence,
G. T. Reddy +7 more
semanticscholar +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
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Epidemiology and ‘big data’ [PDF]
European Journal of Epidemiology, 2017 In the past 70 years, epidemiology has gone through asubstantial development of both methodology and moresophisticated analyses with determinant- and disease-specific elements. Despite the discussion earlier in thisjournal as to whether the duality of epidemiology’sembrace of both research methods and content-based topicsis a positive development [1, 2]
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Big science and big data in nephrology [PDF]
Kidney International, 2019 Published by Elsevier, New York ...
Sáez Rodríguez, Julio +3 more
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Brief introduction of medical database and data mining technology in big data era
Journal of Evidence-Based Medicine, 2020 Data mining technology can search for potentially valuable knowledge from a large amount of data, mainly divided into data preparation and data mining, and expression and analysis of results.
Jin Yang +8 more
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
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Big Data, Big Opportunities, and Big Challenges [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2015 High-throughput assays have begun to revolutionize modern biology and medicine. The advent of cheap next-generation sequencing (NGS) has made it possible to interrogate cells and human populations as never before. Although this has allowed us to investigate the genetics, gene expression, and impacts of the microbiome, there remain both practical and ...
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FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
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JACC: Cardiovascular Interventions, 2016 ![Figure][1] The interventional cardiology course that we began after Andreas Gruentzig joined us 35 years ago continues to evolve. Initially this was the primary exposure for invasive cardiologists desiring to take up the new method of coronary angioplasty.
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