Results 91 to 100 of about 724,460 (303)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Big Data Privacy Scenarios [PDF]

, 2015
This paper is the first in a series on privacy in Big Data. As an outgrowth of a series of workshops on the topic, the Big Data Privacy Working Group undertook a study of a series of use scenarios to highlight the challenges to privacy that arise in the ...
Sollins, Karen, Vernon, Mona, Weitzner, Danny, Bruce, Elizabeth   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

GLEM: a global–local enhancement method for fine-grained image recognition with attention erasure and multi-view cropping

Journal of King Saud University: Computer and Information Sciences
Fine-grained image recognition (FGIR) aims to distinguish between visual objects and their subcategories with subtle differences. Due to the highly similar features between categories in fine-grained image recognition tasks, the model requires more ...
Chenglong Zhou, Damin Zhang, Qing He, MingFang Li, MingRong Li, Xiaobo Zhou   +5 more
doaj   +1 more source

The Politics of Big Data - Principles, policies, practices

, 2018
acceptedVersionLocked until 29.9.2019 due to copyright restrictions. This is an Accepted Manuscript of a book chapter published by Routledge in [The Politics of Big Data.
Sætnan, Ann Rudinow, Schneider, Ingrid, Green, Nicola   +2 more
core  

Big Data : Overview

International Journal of Computer Trends and Technology, 2014
3 pages, 1 ...
Richa Gupta, Sunny Gupta, Anuradha Singhal   +2 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

CAPTURE-24: A large dataset of wrist-worn activity tracker data collected in the wild for human activity recognition

Scientific Data
Existing activity tracker datasets for human activity recognition are typically obtained by having participants perform predefined activities in an enclosed environment under supervision. This results in small datasets with a limited number of activities
Shing Chan, Yuan Hang, Catherine Tong, Aidan Acquah, Abram Schonfeldt, Jonathan Gershuny, Aiden Doherty   +6 more
doaj   +1 more source

Cherry-Net: real-time segmentation algorithm of cherry maturity based on improved PIDNet

Frontiers in Plant Science
IntroductionAccurate identification of cherry maturity and precise detection of harvestable cherry contours are essential for the development of cherry-picking robots. However, occlusion, lighting variation, and blurriness in natural orchard environments
Jie Cui, Jie Cui, Jie Cui, Lilian Zhang, Lilian Zhang, Lilian Zhang, Lutao Gao, Lutao Gao, Lutao Gao, Chunhui Bai, Chunhui Bai, Chunhui Bai, Linnan Yang, Linnan Yang, Linnan Yang   +14 more
doaj   +1 more source