Results 101 to 110 of about 25,203,054 (312)

Big Trials or Big Data

JACC: Cardiovascular Interventions, 2016
![Figure][1] The interventional cardiology course that we began after Andreas Gruentzig joined us 35 years ago continues to evolve. Initially this was the primary exposure for invasive cardiologists desiring to take up the new method of coronary angioplasty.
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Mining "big data" using big data services

International Journal of Internet Science, 2014
While many colleagues within science are fed up with the “big data fad”, empirical analyses we conducted for the current editorial actually show an inconsistent picture: we use big data services to determine whether there really is an increase in writing about big data or even widespread use of the term.
Reips, Ulf-Dietrich, Matzat, Uwe
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

GLEM: a global–local enhancement method for fine-grained image recognition with attention erasure and multi-view cropping

Journal of King Saud University: Computer and Information Sciences
Fine-grained image recognition (FGIR) aims to distinguish between visual objects and their subcategories with subtle differences. Due to the highly similar features between categories in fine-grained image recognition tasks, the model requires more ...
Chenglong Zhou, Damin Zhang, Qing He, MingFang Li, MingRong Li, Xiaobo Zhou   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cherry-Net: real-time segmentation algorithm of cherry maturity based on improved PIDNet

Frontiers in Plant Science
IntroductionAccurate identification of cherry maturity and precise detection of harvestable cherry contours are essential for the development of cherry-picking robots. However, occlusion, lighting variation, and blurriness in natural orchard environments
Jie Cui, Jie Cui, Jie Cui, Lilian Zhang, Lilian Zhang, Lilian Zhang, Lutao Gao, Lutao Gao, Lutao Gao, Chunhui Bai, Chunhui Bai, Chunhui Bai, Linnan Yang, Linnan Yang, Linnan Yang   +14 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Untargeted poisoning attack based on fake clients and its defense in federated learning

Cybersecurity
Untargeted poisoning attacks pose a serious threat to federated learning. However, existing untargeted poisoning attacks have limitations. Most attacks assume that the adversary can control a large number of real clients, which is difficult to achieve in
Caimei Wang, Kangjian Xu, An He, Zhipeng Sun, Jianzhong Pan, Yudong Ren   +5 more
doaj   +1 more source

Research on Precise Segmentation and Center Localization of Weeds in Tea Gardens Based on an Improved U-Net Model and Skeleton Refinement Algorithm

Agriculture
The primary objective of this research was to develop an efficient method for accurately identifying and localizing weeds in ecological tea garden environments, aiming to enhance the quality and yield of tea production.
Zhiyong Cao, Shuai Zhang, Chen Li, Wei Feng, Baijuan Wang, Hao Wang, Ling Luo, Hongbo Zhao   +7 more
doaj   +1 more source