Results 101 to 110 of about 3,434,319 (342)

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

CAPTURE-24: A large dataset of wrist-worn activity tracker data collected in the wild for human activity recognition

Scientific Data
Existing activity tracker datasets for human activity recognition are typically obtained by having participants perform predefined activities in an enclosed environment under supervision. This results in small datasets with a limited number of activities
Shing Chan, Yuan Hang, Catherine Tong, Aidan Acquah, Abram Schonfeldt, Jonathan Gershuny, Aiden Doherty   +6 more
doaj   +1 more source

The SIKS/BiGGrid Big Data Tutorial [PDF]

, 2011
The School for Information and Knowledge Systems SIKS and the Dutch e-science grid BiG Grid organized a new two-day tutorial on Big Data at the University of Twente on 30 November and 1 December 2011, just preceding the Dutch-Belgian Database Day.
Hiemstra, Djoerd, Lammerts, Evert, Vries, Arjen P. de   +2 more
core   +1 more source

BigDataBench: a Big Data Benchmark Suite from Internet Services

, 2014
As architecture, systems, and data management communities pay greater attention to innovative big data systems and architectures, the pressure of benchmarking and evaluating these systems rises.
Gao, Wanling, He, Yongqiang, Jia, Zhen, Li, Xiaona, Lu, Gang, Luo, Chunjie, Qiu, Bizhu, Shi, Yingjie, Wang, Lei, Yang, Qiang, Zhan, Jianfeng, Zhan, Kent, Zhang, Shujie, Zheng, Chen, Zhu, Yuqing   +14 more
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

DAM-Faster RCNN: few-shot defect detection method for wood based on dual attention mechanism

Scientific Reports
In wood defect detection, factors such as few-shot sample scarcity, diverse defect types, and complex background interference severely limit the model’s recognition accuracy and generalization ability.
Xingyu Tong, Zhihong Liang, Mingming Qin, Fangrong Liu, Jiayu Yang, Hengjiang Xiao, Wei Dai   +6 more
doaj   +1 more source

Statistics in the Big Data era [PDF]

, 2016
It is estimated that about 90% of the currently available data have been produced over the last two years. Of these, only 0.5% is effectively analysed and used.
DI CIACCIO, AGOSTINO, GIORGI, Giovanni Maria   +1 more
core  

Profiling Language Learners in the Big Data Era [PDF]

, 1970
Mauro Ocaña, Hassan Khosravi, Aneesha Bakharia   +2 more
openalex   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source