Results 121 to 130 of about 25,747,115 (388)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Routing networking technology based on improved ant colony algorithm in space-air-ground integrated network

EURASIP Journal on Advances in Signal Processing
Space-air-ground integrated networks comprise a multi-level heterogeneous integrated network that combines satellite-based, aerial, and terrestrial networks.
Wuzhou Nie, Yong Chen, Yuhao Wang, Peizheng Wang, Meng Li, Lei Ning   +5 more
doaj   +1 more source

How Can the Development of Digital Economy Empower Green Transformation and Upgrading of the Manufacturing Industry?—A Quasi-Natural Experiment Based on the National Big Data Comprehensive Pilot Zone in China [PDF]

, 2023
Qiansheng Gong, Xiangyu Wang, Xi Tang
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Clustering ensemble pruning algorithm based on vec2vec classifier representation

Journal of King Saud University: Computer and Information Sciences
The complementarity of ensemble learning primarily stems from the diversity among its classifier members, which is typically assessed by calculating the similarity or distance between classifiers.
Chunlong Li, Danyang Li, Xue Qin, Yuanxian Qin, Jialin Li, Jiafan Yuan   +5 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Cherry-Net: real-time segmentation algorithm of cherry maturity based on improved PIDNet

Frontiers in Plant Science
IntroductionAccurate identification of cherry maturity and precise detection of harvestable cherry contours are essential for the development of cherry-picking robots. However, occlusion, lighting variation, and blurriness in natural orchard environments
Jie Cui, Jie Cui, Jie Cui, Lilian Zhang, Lilian Zhang, Lilian Zhang, Lutao Gao, Lutao Gao, Lutao Gao, Chunhui Bai, Chunhui Bai, Chunhui Bai, Linnan Yang, Linnan Yang, Linnan Yang   +14 more
doaj   +1 more source

Big Data in Education: Perception of Training Advisors on Its Use in the Educational System [PDF]

, 2020
Julio Ruiz‐Palmero, Ernesto Colomo Magaña, José Manuel Ríos Ariza, Melchor Gómez García   +3 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

GLEM: a global–local enhancement method for fine-grained image recognition with attention erasure and multi-view cropping

Journal of King Saud University: Computer and Information Sciences
Fine-grained image recognition (FGIR) aims to distinguish between visual objects and their subcategories with subtle differences. Due to the highly similar features between categories in fine-grained image recognition tasks, the model requires more ...
Chenglong Zhou, Damin Zhang, Qing He, MingFang Li, MingRong Li, Xiaobo Zhou   +5 more
doaj   +1 more source