Results 181 to 190 of about 25,747,115 (388)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

View-label driven cross-space structure alignment for incomplete multi-view partial multi-label classification

open access: yesJournal of King Saud University: Computer and Information Sciences
Despite significant advancements in multi-view multi-label learning driven by its broad applicability, real-world scenarios frequently suffer from dual incompleteness in both view and label spaces due to data acquisition uncertainties. The incompleteness
Shenrun Ding   +4 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

A refined lion optimizer for deep learning

open access: yesScientific Reports
Optimization algorithms play a fundamental role in training neural networks. The optimizer focuses on the updating weights of momentum and velocity on learning rates and losses, furthermore the complexity of the optimizer and the quantity of updated ...
Jian Rong   +4 more
doaj   +1 more source

Hybrid Attention Fusion Embedded in Transformer for Remote Sensing Image Semantic Segmentation

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In the context of fast progress in deep learning, convolutional neural networks have been extensively applied to the semantic segmentation of remote sensing images and have achieved significant progress.
Yan Chen   +8 more
doaj   +1 more source

Philosophical Aspects of Big Data [PDF]

open access: yes
Big Data can generate, through inferences, new knowledge and perspectives. The paradigm that results from using Big Data creates new opportunities. Big Data has great influence at the governmental level, positively affecting society. These systems can be
Sfetcu, Nicolae
core  

Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource [PDF]

open access: gold, 2016
Hongseok Shim   +7 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

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