Results 221 to 230 of about 26,034,833 (395)

“Set of Strings” Framework for Big Data Modeling

, 2019
Igor A. Sheremet
openalex   +2 more sources

Big Data Techniques for Applied Geoscience: Compute and Communicate [PDF]

, 2016
Anya M. Reading, Matthew J. Cracknell, Stephen Kuhn   +2 more
openalex   +1 more source

Why Big Data = Big Deal [PDF]

Big Data, 2014
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Blockchain Technology for Big-data Sharing in Material Genome Engineering. [PDF]

Sci Data
Wang R, Ye F, Tang S, Zhang H, He J, Zhang X, Xu C.   +6 more
europepmc   +1 more source

Trust and Distrust: On Sense and Nonsense in Big Data

, 2019
Stefan Raß, Andreas Schorn, Florian Skopik   +2 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Rise of Big Data in Spine Surgery Research: A Bibliometric Analysis, 1993-2024. [PDF]

Cureus
Gerstmeyer J, Gorbacheva A, Pierre C, Von Glinski A, Heffernan T, Jouppi L, Godolias P, Schildhauer TA, Abdul-Jabbar A, Oskouian RJ, Chapman J.   +10 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Big Data Analytics and Machine Learning for Smart Agriculture [PDF]

openalex   +1 more source