Results 231 to 240 of about 26,034,833 (395)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Exploring the influence of circular economy on big data analytics and supply chain resilience nexus: A structural equation modeling approach

Samia Islam, S.Z. Hassan, Sourav Hossain, Tazim Ahmed, Chitra Lekha Karmaker, A.B.M. Mainul Bari   +5 more
openalex   +1 more source

Design and Implementation of a Flood Disaster Safety System Using Realtime Weather Big Data

, 2017
Yeonwoo Kim, Byoung‐Hoon Kim, Geonsik Ko, Minwoong Choi, Heesub Song, Gihoon Kim, Seunghun Yoo, Jongtae Lim, Kyungsoo Bok, Jaesoo Yoo   +9 more
openalex   +1 more source

Big data analytics and firm performance: Effects of dynamic capabilities

, 2017
S. Wamba, A. Gunasekaran, Shahriar Akter, S. Ren, Rameshwar Dubey, S. Childe   +5 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Big data in modelling geographical accessibility to healthcare: a scoping review protocol. [PDF]

BMJ Open
Njogu A, Libertini L, Avahoundjè EM, Grovogui FM, Ba OA, Ray N, Beňová L, Macharia PM.   +7 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Spatial differentiation in public perception of peak summer heat based on microblog big data. [PDF]

PLoS One
Sheng Y, Zhen J, Zhang Y, Li D.
europepmc   +1 more source

Big Data Anonymization Requirements vs Privacy Models

, 2018
Josep Domingo‐Ferrer
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source