Results 241 to 250 of about 3,434,319 (342)

Leveraging Big Data and Business Analytics [Guest editors' introduction] [PDF]

, 2013
Sunil Mithas, Maria R. Lee, Seth Earley, San Murugesan, Reza Djavanshir   +4 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Empirical evidence and role mechanisms of big data enabling corporate green development. [PDF]

Sci Rep
Wang Y, Li Y, Ruan Z, Tang Z, Gao T.
europepmc   +1 more source

Statistical Thinking: From “Small data” to “Big data”

, 2012
Kiranmoy Das
openalex   +1 more source

Big Data, Big Problems?

TATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2016
openaire   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Big-Data Analysis of Geometric Descriptors as Efficient Predictors of Energetic Stability in Nonplanar Polycyclic Aromatic Hydrocarbons. [PDF]

J Comput Chem
Gregory KP, Karton A.
europepmc   +1 more source

The Abzooba Smart Health Informatics Platform (SHIP) TM - From Patient Experiences to Big Data to Insights

, 2012
Naveen Ashish, Antarip Biswas, Sumit Das, Saurav Nag, Rajiv Pratap   +4 more
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Spatial heterogeneity of built environment's impact on urban vitality using multi-source big data and MGWR. [PDF]

Sci Rep
Wu W, Liu X, Zhou Y, Zhao K.
europepmc   +1 more source