Results 271 to 280 of about 25,420,692 (388)

Global trends of big data analytics in health research: a bibliometric study. [PDF]

Front Med (Lausanne)
Yao L, Liu Y, Wang T, Han C, Li Q, Li Q, You X, Ren T, Wang Y.   +8 more
europepmc   +1 more source

Computational Earth Science: Big Data Transformed Into Insight [PDF]

, 2013
Scott Sellars, Phu Nguyen, Wei Chu, Xiaogang Gao, Kuolin Hsu, Soroosh Sorooshian   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Integrating big data and artificial intelligence to predict progression in multiple sclerosis: challenges and the path forward. [PDF]

J Neuroeng Rehabil
Khan H, Aerts S, Vermeulen I, Woodruff HC, Lambin P, Peeters LM.   +5 more
europepmc   +1 more source

Big Data Analysis of Software Performance Trend using SPC with Flexible Moving Window and Fuzzy Theory

, 2012
Dong-Hun Lee, Jong‐Jin Park
openalex   +2 more sources

Heart beats in the cloud: distributed analysis of electrophysiological ‘Big Data’ using cloud computing for epilepsy clinical research [PDF]

, 2013
Satya S. Sahoo, Catherine Jayapandian, Gaurav Garg, Farhad Kaffashi, Stephanie Chung, Alireza Bozorgi, Chien-Hun Chen, Kenneth A. Loparo, Samden Lhatoo, Guo‐Qiang Zhang   +9 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Development of a big data platform for collecting and utilizing clinical information from the Korea Biobank Network. [PDF]

BMC Med Inform Decis Mak
Im YS, Oh SW, Kim KH, Choi W, Choi IY.
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Medical Big Data Storage in Precision Medicine: A Systematic Review. [PDF]

J Biomed Phys Eng
Langarizadeh M, Hajebrahimi M.
europepmc   +1 more source