Results 41 to 50 of about 115,029 (313)

Case studies to illustrate data wrangling approaches and share R scripts [PDF]

, 2022
These case studies are stable and widely available for uptake, and have been used in training workshops covering data processing and analysis using R, organized under Module 1 of the Big Data ...
CGIAR Platform for Big Data in Agriculture
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Phylodynamics and molecular epidemiology of the respiratory syncytial virus fusion protein in China

Microbiology Spectrum
Respiratory syncytial virus (RSV) infections have a high prevalence in young children, immunocompromised adults, and elderly, raising global concerns. Global RSV surveillance infers an 8%–27% mortality rate in preterm-born children, with 2.8 million/year.
Muhammad Nabeel Amjad, Jing Wang, Bei Shen, Huiting Xu, Muhammad Awais Ashraf, Muhammad Asif Raza, Ghayyas ud Din, Lingdie Chen, Ahsan Ali Bhutto, Lihuan Yue, Hammad ul Hussan, Dan Qian, Wei Dong, Huajie Yan, Yihong Hu   +14 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Unlocking influenza B: exploring molecular biology and reverse genetics for epidemic control and vaccine innovation

Virology Journal
Influenza is a highly contagious acute viral illness that affects the respiratory system, posing a significant global public health concern. Influenza B virus (IBV) causes annual seasonal epidemics.
Ghayyas Ud Din, Chunchen Wu, Zahra Tariq, Kinza Hasham, Muhammad Nabeel Amjad, Bei Shen, Lihuan Yue, Muhammad Asif Raza, Muhammad Awais Ashraf, Lingdie Chen, Yihong Hu   +10 more
doaj   +1 more source

A comprehensive review of influenza B virus, its biological and clinical aspects

Frontiers in Microbiology
Influenza B virus (IBV) stands as a paradox, often overshadowed by its more notorious counterpart, influenza A virus (IAV). Yet, it remains a captivating and elusive subject of scientific inquiry.
Muhammad Awais Ashraf, Muhammad Awais Ashraf, Muhammad Asif Raza, Muhammad Asif Raza, Muhammad Nabeel Amjad, Muhammad Nabeel Amjad, Ghayyas ud Din, Ghayyas ud Din, Lihuan Yue, Bei Shen, Lingdie Chen, Lingdie Chen, Wei Dong, Huiting Xu, Yihong Hu, Yihong Hu   +15 more
doaj   +1 more source

Big Data Platforms and Techniques

Indonesian Journal of Electrical Engineering and Computer Science, 2016
Data is growing at unprecedented rate and has led to huge volume generated; the data sources include mobile, internet and sensors. This voluminous data is generated and updated at high velocity by batch and streaming platforms. This data is also varied along structured and unstructured types.
Borodo, S. M., Shamsuddin, S. M., Hasan, S.   +2 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

CGIAR Platform for Big Data in Agriculture - Plan of Work and Budget 2020

, 2020
The Platform for Big Data in Agriculture works towards outcomes demonstrating that CGIAR —as a more unified System—has claimed a leadership position in the evolving digital agriculture landscape.
CGIAR Platform for Big Data in Agriculture
core