Results 111 to 120 of about 8,175,112 (344)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Big Five factors and personality traits
Хабаршы. Психология және социология сериясы, 2018 The article researches is devoted to five core personality traits. Evidence of this theory has been grow-ing for many years, beginning with the research of D. W.
Zhou Jingli
doaj +2 more sources
Personalidade e sinestesia: estudo de caso com métodos projetivos [PDF]
Avaliação PsicológicaRESUMO Embora haja indícios de traços de personalidade relacionados à sinestesia, não há evidências de estudos utilizando métodos projetivos. Considerando peculiaridades perceptivas associadas ao fenômeno e seu possível impacto na utilização desses ...
Pietra Diovanna Saladini de Cecco +1 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Relationship between personality traits, reading tendencies, and empathy
International Journal of Personality PsychologyLiterature suggests that reading fiction, more than reading nonfiction, correlates positively with the reader's social cognition, chiefly cognitive empathy.
Terezija Buljan, Boris Mlačić
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Civil Procedure’s Five Big Ideas
SSRN Electronic Journal, 2011 Article published in the Michigan State Law Review.
openaire +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source