Results 111 to 120 of about 2,805,991 (295)

Academia's Big Five

open access: yesF1000Research, 2019
This paper proposes a normative taxonomy by which universities can express the extent to which they meet five core epistemic responsibilities. Epistemic responsibilities are responsibilities that have to do with the attainment of knowledge and understanding.
Peels, Rik   +3 more
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Banking in Japan: Will "Too Big To Fail" Prevail? [PDF]

open access: yes
This paper reviews the evolution of the Japanese banking sector and the development of the banking crisis in Japan in the context of "too big to fail." It describes the deterioration of the Japanese financial sector caused by the bad loan problems and ...
Rixtel, Adrian van   +3 more
core  

Weighing the string mass with the COBE data [PDF]

open access: yes, 1998
In the context of the pre-big bang scenario the large-scale CMB anisotropy can be seeded by a primordial background of very light (or massless) axion fluctuations.
Gasperini, M.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Relationship Between Intelligence and Personality Traits Differentiated by Gender in Spanish Adolescents

open access: yesChildren
Background/Objectives: Intelligence and personality are the most researched constructs in the scientific literature in the field of psychology. Also, the relationship between them has been studied, with controversial results.
Ricardo Quintero   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Alexithymia measured with the TAS-20 questionnaire: Determining the validity of the factor structure and its relation to life satisfaction and the Big Five personality traits [PDF]

open access: yesPsihološka Istraživanja, 2018
Alexithymia is the inability of an individual to recognize their own or someone else's feelings and to communicate their own emotional states. On the cognitive level, we can observe a decreased ability for imagination and a practical style of thinking ...
Rokvić Nikola, Jovanović Tamara
doaj  

USING BIG BOOK TO TEACH KINDS OF ANIMAL [PDF]

open access: yes, 2018
Big book is one kind of media for teaching especially for reading aloud activity. In here, children will be taught about kinds of animal. The subjects are five students of Bina Prestasi Courses located in Gunung gangsir, Pasuruan.
apsari, anggi
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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