Results 81 to 90 of about 2,723,374 (349)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Female labor force participation and the big five [PDF]

open access: yes
This paper investigates the relationship between personality traits and female labor force participation. While research on the role of cognitive skills for individual labor market success has a long tradition in economics, comparatively little is known ...
Pohlmeier, Winfried, Wichert, Laura
core  

Erratum: The big five and big two personality factors in Mongolia

open access: yesFrontiers in Psychology, 2022
Frontiers Production Office
doaj   +1 more source

Personalidade e sinestesia: estudo de caso com métodos projetivos [PDF]

open access: yesAvaliação Psicológica
RESUMO Embora haja indícios de traços de personalidade relacionados à sinestesia, não há evidências de estudos utilizando métodos projetivos. Considerando peculiaridades perceptivas associadas ao fenômeno e seu possível impacto na utilização desses ...
Pietra Diovanna Saladini de Cecco   +1 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

New and old mosquito records for extreme southern Florida (Diptera: Culicidae) [PDF]

open access: yes, 2009
New locality records for Culiseta inornata (Williston) are reported from Big Pine Key, Grassy Key, and No Name Key in Monroe County, Florida. Five specimens were collected in dry ice-baited light traps.
Hribar, Lawrence J.
core  

ANALISIS PENGARUH THE BIG FIVE PERSONALITY TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) DAN KINERJA PERAWAT DI RS SANTA CLARA MADIUN

open access: yesJurnal Manajemen Indonesia, 2017
Nurse performance shows the magnitude of the contribution made by nurses to hospital and reflects the performance of a hospital because patient will often relates and meets the nurse.
Desi Natalia Soepono   +1 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

On base point free theorem and Mori dream spaces for log canonical threefolds over the algebraic closure of a finite field

open access: yes, 2016
The authors and D. Martinelli proved the base point free theorem for big line bundles on a three-dimensional log canonical projective pair defined over the algebraic closure of a finite field.
Nakamura, Yusuke, Witaszek, Jakub
core   +1 more source

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