Results 81 to 90 of about 7,223,865 (302)

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Industrial Big Data Analytics: Challenges, Methodologies, and Applications [PDF]

open access: yesarXiv, 2018
While manufacturers have been generating highly distributed data from various systems, devices and applications, a number of challenges in both data management and data analysis require new approaches to support the big data era. These challenges for industrial big data analytics is real-time analysis and decision-making from massive heterogeneous data
arxiv  

USING BIG BOOK TO TEACH KINDS OF ANIMAL [PDF]

open access: yes, 2018
Big book is one kind of media for teaching especially for reading aloud activity. In here, children will be taught about kinds of animal. The subjects are five students of Bina Prestasi Courses located in Gunung gangsir, Pasuruan.
apsari, anggi
core  

Who Is Prejudiced, and Toward Whom? The Big Five Traits and Generalized Prejudice

open access: yesPersonality and Social Psychology Bulletin, 2019
Meta-analyses show that low levels of Openness and Agreeableness correlate with generalized prejudice. However, previous studies narrowly assessed prejudice toward low-status, disadvantaged groups.
Jarret T. Crawford, M. Brandt
semanticscholar   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

open access: yesAging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen   +3 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

On two recent extensions of the Big Five of Reverse Mathematics [PDF]

open access: yesarXiv
The program Reverse Mathematics in the foundations of mathematics seeks to identify the minimal axioms required to prove theorems of ordinary mathematics. One always assumes the base theory, a logical system embodying computable mathematics. As it turns out, many (most?) theorems are either provable in said base theory, or equivalent to one of four ...
arxiv  

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Longitudinal predictors of weapon involvement in middle adolescence: Evidence from the UK Millennium Cohort Study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 5-14, January 2023., 2023
Abstract This study uses longitudinal data from the UK Millennium Cohort Study (N = 13,277) to examine the childhood and early adolescence factors that predict weapon involvement in middle adolescence, which in this study is exemplified by having carried or used a weapon.
Aase Villadsen, Emla Fitzsimons
wiley   +1 more source

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