Results 231 to 240 of about 2,079,448 (298)

Elastic Graphene‐Shell Architectures Enable Stress Regulation in High‐Capacity Lithium‐Ion Battery Electrodes

Advanced Science, EarlyView.
In this study, we developed elastic hollow graphene spheres (GS) that serve as a pore‐engineering additive. This strategy enables the direct fabrication of porous electrodes, effectively mitigating volume expansion and mechanical stress in silicon‐based anodes during cycling without compromising active material or increasing production costs.
Luwen Li, Qitao Shi, Zhipeng Wang, Cheng Zhang, Jiaqi Wang, Xiaoqin Yang, Alicja Bachmatiuk, Chen Lu, Ruizhi Yang, Yanbin Shen, Mark H. Rümmeli   +10 more
wiley   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

Advanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu, Jiqing Wang, Zhiyun Hao, Mingna Li, Huimin Zhen, Yuan Liu, Guoyong Zhao, Chunyan Ren, Xuelan Zhou, Haixiong Hu, Mingjie Li, Nan Shi   +11 more
wiley   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

Advanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai, Bei Wang, Mingmin Shi, Dianwei Liu, Huimin Ji, Ting Wang, Ziwei Wang, Kaiming Guo, Xinyang Dou, Chunyan Qian, Fang Zhang, Yongming Wang, Hongju Mao, Rui Wang   +13 more
wiley   +1 more source

Independent Discovery of <i>Mesomycoplasma conjunctivae</i> in Non-Native Aoudad (<i>Ammotragus lervia</i>) in Texas. [PDF]

Animals (Basel)
Wright EA, Amman BR, Beck WI, Phillips CD, Bradley RD.   +4 more
europepmc   +1 more source

First, Do NoHarm: How Pharmaceutical AI Is Improving Care Across Brazil. [PDF]

J Med Internet Res
Taylor L.
europepmc   +1 more source

The TEMPO program and the future of digital mental health regulation in the US. [PDF]

NPJ Digit Med
Parks AC, Shick A.
europepmc   +1 more source

A study of individual and market level factors to estimate key determinants of financial success among solopreneurs. [PDF]

Sci Rep
Hagenauer W, Zipko HT.
europepmc   +1 more source