Results 181 to 190 of about 21,955 (321)

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Unveiling human–wildlife interactions in the context of livestock grazing abandonment and the return of large carnivores, ungulates and vultures: A stakeholder perspective

People and Nature, EarlyView.
Abstract Pastoral practices remain a widespread economic activity across European mountain regions. However, the viability of this activity may be threatened by the recovery of large wild vertebrates associated with passive rewilding, leading to the so‐called human–wildlife conflicts.
P. Acebes, F. J. Muñoz‐Gálvez, Z. Iglesias‐González, M. García‐Llorente, D. López‐García   +4 more
wiley   +1 more source

Optimal Subsampling Methods in Bike Sharing Data Analysis [PDF]

, 2021
Xiaofeng Zhao
openalex   +1 more source

What does coexistence mean? Insight from place‐based trajectories of pastoralists and bears encounters in the Pyrenees

People and Nature, EarlyView.
Abstract The recovery of large carnivores in Europe raises issues related to sharing landscape with humans. Beyond technical solutions, it is widely recognized that social factors also contribute to shaping coexistence. In this context, scholars increasingly stress the need to adopt place‐based approaches by analysing how humans and wildlife interact ...
Alice Ouvrier, Manon Culos, Sylvie Guillerme, Antoine Doré, Helene Figari, John D. C. Linnell, Pierre‐Yves Quenette, Ruppert Vimal   +7 more
wiley   +1 more source

An interval-valued Pythagorean fuzzy TOPSIS approach for service quality evaluation of bike-sharing providers under uncertain environment. [PDF]

Sci Rep
Chai N, Chen Z, Zhou W, Zhang S.
europepmc   +1 more source

A new RNN based machine learning model to forecast COVID-19 incidence, enhanced by the use of mobility data from the bike-sharing service in Madrid. [PDF]

Heliyon, 2023
Muñoz-Organero M, Callejo P, Hombrados-Herrera MÁ.   +2 more
europepmc   +1 more source

Business plan for green shared electric bikes in Nanjing, Jiangsu, China [PDF]

Zhilin Li
openalex   +1 more source

Multi-task supply-demand prediction and reliability analysis for docked bike-sharing systems via transformer-encoder-based neural processes

, 2023
Meng Xu, Yining Di, Hai Yang, Xiqun Chen, Zheng Zhu   +4 more
openalex   +1 more source

Using participatory scenario planning to explore the synergies and trade‐offs from upland treescape expansion

People and Nature, EarlyView.
Abstract The future of land use in the UK uplands is highly debated, with growing interest in increasing tree cover and other land use changes, alongside a desire to maintain traditional land use patterns and practices. Treescape expansion is likely to result in synergies and trade‐offs between different outcomes, so integrating stakeholder preferences
Melissa Minter, Susan Baker, Euan Bowditch, Sheena Carlisle, Natasha Constant, Alix Syder, Tom Finch   +6 more
wiley   +1 more source

Excess demand prediction for bike sharing systems. [PDF]

PLoS One, 2021
Liu X, Pelechrinis K.
europepmc   +1 more source