Results 71 to 80 of about 3,593,458 (250)

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Ausencia de la mutación BRCA1 del (exones 9-12) en familias con cáncer de seno / ovario fuera de hispanos mexicanos [PDF]

, 2009
3 páginasThe frequency and spectrum of germ line mutations in the high-penetrance breast cancer susceptibility genes BRCA1 and BRCA2 shows considerable variation by ethnic group.
Seidel Renkert, Antje, Colombian Breast Cancer Study Group (COLBCS), Torres, Diana, Seidel-Renkert, Antje, Rashid, Muhammad U., Briceño Balcázar, Ignacio, Weitzel, Jeffrey N., Hamann, Ute, Briceno, Ignacio   +8 more
core   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Clinicopathological characteristics and prognosis of synchronous bilateral breast cancer [PDF]

Waike lilun yu shijian
Objective To analyze the clinicopathological characteristics and prognosis of primary synchronous bilateral breast cancer (SBBC) based on Shanghai Jiao Tong University Breast Cancer Database, and to explore risk factors of prognosis.
CHEN Yuanyuan, WANG Jie, CHEN Fang
doaj   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Bilateral Synchronous Male Breast Cancer in Iran: A Case Report

Middle East Journal of Cancer, 2016
Bilateral synchronous male breast cancer is very rare. A 63-year-old male presented with rapidly progressive enlarging bilateral breast masses without ulceration and bloody nipple discharge.
Vahid Zangouri, Mohammad Yasin Karami, Maral Mokhtari, Majid Akrami, Sedighe Tahmasebi, Abdolrasoul Talei, Mehrnoosh Maalhagh   +6 more
doaj  

The feasibility of endoscopy-assisted breast conservation surgery for patients with early breast cancer [PDF]

, 2011
PURPOSE: Breast conservation surgery (BCS) has become a standard treatment method for patients with early breast cancer. Endoscopy-assisted BCS (EABCS) can be performed through an inconspicuous periareolar and a small axillary incision for sentinel node ...
이준상, Seho Park, 박형석, Seung-Il Kim, 김승일, Hyung Seok Park, Byeong-Woo Park, Jong Seok Lee, 이종석, Jun Sang Lee, 박병우, 박세호   +11 more
core   +1 more source

Bilateral breast metastases from anaplastic lymphoma kinase-positive lung cancer in a male: a case report

Journal of Medical Case Reports
Background Distant metastases from lung cancer are commonly found in the brain, bone, and liver. Metastases to the breast from non-mammary malignancies are extremely rare, and their clinical presentations remain unclear.
Sumire Koh, Yumiko Koi, Wakako Tajiri, Junji Kawasaki, Sayuri Akiyoshi, Yoshiaki Nakamura, Chinami Koga, Tatsuro Okamoto, Kenichi Taguchi, Eriko Tokunaga   +9 more
doaj   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source