Results 91 to 100 of about 277,238 (258)
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source
Time series expansion using discrete bilateral Laguerremodels
The modelling of signals with Laguerre functions is considered. The main contribution concerns the possibility of handling signals defined both in the negative and the positive time domains; this has a potential application to the identification of processes involving inputs and outputs whose knowledge is available near the time origin or for noncausal
Ekongolo, Simon Bebe +2 more
openaire +1 more source
The Mind From Within: Visceral Roots of Human Cognition
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti +1 more
wiley +1 more source
Acute bilateral toxic endothelitis in binge alcohol consumption – A case series
Endothelitis has a vast range of etiologies, including infective, chemical-induced, drug-induced, systemic, and toxic causes. Toxic endothelitis secondary to alcohol binge consumption is rare and is reported less frequently in the literature. We report a
Rakhi D’cruz, Aravind Roy
doaj +1 more source
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña +7 more
wiley +1 more source
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin +13 more
wiley +1 more source
Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao +11 more
wiley +1 more source
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou +16 more
wiley +1 more source
Bilateral acute intermediate uveitis following intrauterine Chitosan tamponade: a case series
Background Postpartum hemorrhage is a leading cause of maternal morbidity and mortality, with intrauterine tamponade techniques increasingly employed in its management.
David Beckers +6 more
doaj +1 more source

