Results 31 to 40 of about 677 (269)

Searching for Solid Ground in Polish-American Relations in the Second Year of the Trump Administration

open access: yesInternational Studies: Interdisciplinary Political and Cultural Journal, 2019
Since the beginning of the Trump Administration, analysts of American foreign policy have observed several changes in the style substance and style of Washington’s international behavior with regard to both foes and friends.
Bohdan Szklarski, Piotr Ilowski
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Bad Concepts, Bilateral Contents

open access: yesErgo, An Open Access Journal of Philosophy, 2022
I argue that one need not be an inferentialist in order to model inconsistent concepts, contrary to what some have thought. Representationalists can do so by adopting a form of bilateralism about contents.
Michael Deigan
doaj   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Paradox of Unilateralism: Institutionalizing Failure In U.S.-Mexican Drug Strategies

open access: yesNorteamérica, 2013
Realism posits that strong states use compulsory power to influence the behavior of weaker ones. If true, then U.S. policy toward Mexico on a key national security issue such as drugs should illustrate that claim and policy outcomes should reflect U.S ...
Simon Reich, Mark Aspinwall
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Bilateral paraganglioma [PDF]

open access: yesBMJ Case Reports, 2012
A 41-year-old man presented with bilateral, painless, non-pulsatile left-sided neck swelling. This was noticed incidentally on a routine medical check-up. He had no significant medical history and did not take any regular medications. Urinary catecholamines and routine blood tests were all normal, and when he had been examined he was normotensive.
Rushikesh Yogesh, Trivedi   +1 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Türkiye’s transregionalism with South Asia: Geoculture-boosted multifaceted bilateralism

open access: yesOASIS, 2023
El transregionalismo se relaciona con interacciones más laxas y menos institucionales, que funcionan a través de actores tanto estatales como no estatales.
Gurol Baba
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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