Results 41 to 50 of about 10,150 (318)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

The Paradox of Unilateralism: Institutionalizing Failure In U.S.-Mexican Drug Strategies

open access: yesNorteamérica, 2013
Realism posits that strong states use compulsory power to influence the behavior of weaker ones. If true, then U.S. policy toward Mexico on a key national security issue such as drugs should illustrate that claim and policy outcomes should reflect U.S ...
Simon Reich, Mark Aspinwall
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Türkiye’s transregionalism with South Asia: Geoculture-boosted multifaceted bilateralism

open access: yesOASIS, 2023
El transregionalismo se relaciona con interacciones más laxas y menos institucionales, que funcionan a través de actores tanto estatales como no estatales.
Gurol Baba
doaj   +1 more source

Bilateralism: Negations, Implications and some Observations and Problems about Hypotheses [PDF]

open access: yes, 2017
This short paper has two loosely connected parts. In the first part, I discuss the difference between classical and intuitionist logic in relation to different the role of hypotheses play in each logic.
Kürbis, Nils
core  

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter   +17 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

China’s Soft Power Diplomacy in Southeast Asia

open access: yesThe Copenhagen Journal of Asian Studies, 2008
The paper analyses the new geo-political and geo-economic strategic relationship between China and Southeast Asia. Is Chinese soft power encroachment into Southeast Asia creating greater stability, does it jeopardize US interests and what is the impact ...
Johannes Dragsbaek Schmidt
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

BILATERAL CHYLOTHORAX

open access: yesBritish Journal of Anaesthesia, 1991
A 2.5-kg female developed bilateral chylothoraces 10 days after surgery for coarctation of the aorta. Initial conservative management consisted of intermittent positive pressure ventilation, drainage of chylous fluid and enteral feeding, but there was no diminution in loss of chyle.
P, Cooper, M L, Paes
openaire   +2 more sources

Home - About - Disclaimer - Privacy