Results 161 to 170 of about 1,013,035 (362)
Gut MicrobesThe small intestine is a key site for nutrient sensing and host–microbiota interactions, yet how it functionally adapts to dietary changes remains poorly understood.
Axel Ranson +15 more
doaj +1 more source
Diagnostic work-up of bile duct strictures: European Society of Gastrointestinal Endoscopy (ESGE) Guideline [PDF]
Antonio Facciorusso +18 more
openalex +1 more source
The role of bile acids in the increased incidence of colorectal cancer in cholecystectomized patients [PDF]
, 2023 Eleonóra Gál +10 more
openalex +1 more source
Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA
Advanced Science, EarlyView.We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang +12 more
wiley +1 more source
THU142 One-year Change In Bile Acids And Its Association With Changes In Metabolic Profile After Sleeve Gastrectomy In Youth [PDF]
, 2023 Shubhangi Tuli +4 more
openalex +1 more source
Advanced Science, EarlyView.The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan +13 more
wiley +1 more source
Effect of excessive saccharose administration on metabolic processes in the liver of rabbits with restricted mobility [PDF]
The administration of saccharose (3 g per 1 kg for 2 months) intensified changes encountered in hypokinesia. There was a more marked increase in the content of cholesterol, pre-beta and beta-lipoproteins, phospholipids, and glycosaminoglycans in the ...
Rylnikov, Y. P.
core +1 more source
Advanced Science, EarlyView.Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu +12 more
wiley +1 more source
Very long O-antigen chains enhance fitness during Salmonella-induced colitis by increasing bile resistance. [PDF]
, 2012 Intestinal inflammation changes the luminal habitat for microbes through mechanisms that have not been fully resolved. We noticed that the FepE regulator of very long O-antigen chain assembly in the enteric pathogen Salmonella enterica serotype ...
Bäumler, Andreas J +6 more
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