Role of Bile Acids and Bile Salts in Acute Pancreatitis
Pancreas, 2021 Abstract Acute pancreatitis (AP) is one of the most common gastroenterological disorders leading to hospitalization. It has long been debated whether biliary AP, about 30% to 50% of all cases, is induced by bile acids (BAs) when they reach the pancreas via reflux or via the systemic blood circulation.
Tran, Quang Trung +13 more
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Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts [PDF]
Journal of Biological Chemistry, 2019 The fish olfactory receptor ORA family is orthologous to the mammalian vomeronasal receptors type 1. It consists of six highly conserved chemosensory receptors expected to be essential for survival and communication. We deorphanized the zebrafish ORA family in a heterologous cell system. The six receptors responded specifically to lithocholic acid (LCA)
Xiaojing Cong +9 more
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Dependence of the biliary excretion of iopanoic acid on bile salts
Gastroenterology, 1978 Abstract Iopanoic acid is an iodinated organic acid used extensively as a radiographic contrast material for oral cholecystography. Like bilirubin, it is conjugated predominately with glucuronic acid in the liver, and the biliary excretion is enhanced by the concomitant biliary excretion of bile salts.
P M, Loeb, J L, Barnhart, R N, Berk
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Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression [PDF]
Pharmaceutical Research, 2020 The bile salt export pump (BSEP), a key player in hepatic bile acid clearance, has been the center of research on drug-induced cholestasis. However, such studies focus primarily on the direct inhibition of BSEP, often overlooking the potential impact of transcriptional repression.
Brandy Garzel +9 more
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Bile salt hydrolase catalyses formation of amine-conjugated bile acids
NatureAbstract Bacteria in the gastrointestinal tract produce amino acid bile acid amidates that can affect host-mediated metabolic processes 1–6 ; however, the bacterial gene(s) responsible for their production remain unknown.
Bipin Rimal +29 more
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Bile Salt Hydrolase-Competent Probiotics in the Management of IBD: Unlocking the “Bile Acid Code”
Nutrients, 2022 Bile acid (BA) species and the gut microbiota (GM) contribute to intestinal mucosa homeostasis. BAs shape the GM and, conversely, intestinal bacteria with bile salt hydrolase (BSH) activity modulate the BA pool composition. The mutual interaction between BAs and intestinal microorganisms also influences mucosal barrier integrity, which is important for
Raffaella Maria Gadaleta +3 more
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Bile Salt Hydrolase Catalyses Formation of Amine-Conjugated Bile Acids
, 2023 Data, and codes to generate figures in Bile Salt Hydrolase Catalyses Formation of Amine-Conjugated Bile Acids .
Rimal, Bipin +2 more
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Effect of Bile, Sodium Salts of Bile Acids, and Unsaturated Fatty Acids on Bacteriophagic Action.
Experimental Biology and Medicine, 1927 Previous investigators record different observations on the effect of bile on bacteriophagic action. Hauduroy,1 Jong and Hauduroy,2 and d'Herelle3 found that bile was decidedly inhibitory, whereas Caublot,4 in observations extending over a period of two years, obtained no evidence of an inhibitory action of bile on bacteriophage.In the studies ...
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Studies in the bile acids. 3. The conjugated bile salts of certain primates [PDF]
Biochemical Journal, 1958 H S, WIGGINS, I D, WOOTTON
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Comparative studies of 'bile salts'. 2. Pythocholic acid [PDF]
Biochemical Journal, 1951 G A D, HASLEWOOD, V M, WOOTTON
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