Results 1 to 10 of about 63,714 (388)

The effect of bile acids on the growth and global gene expression profiles in Akkermansia muciniphila

Applied Microbiology and Biotechnology, 2020
Akkermansia muciniphila is a prominent member of the gut microbiota and the organism gets exposed to bile acids within this niche. Several gut bacteria have bile response genes to metabolize bile acids or an ability to change their membrane structure to ...
T. Hagi, Sharon Y. Geerlings, Bart Nijsse, C. Belzer   +3 more
semanticscholar   +1 more source

Bile resistance mechanisms in Lactobacillus and Bifidobacterium

Frontiers in Microbiology, 2013
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Most of the probiotic bacteria currently available in the market belong to the genera Lactobacillus and Bifidobacterium, and specific ...
Lorena eRuiz, Abelardo eMargolles, Borja eSánchez   +2 more
doaj   +1 more source

New Kids on the Block: Bile Salt Conjugates of Microbial Origin

Metabolites, 2022
Biotransformation of host bile salts by gut microbes results in generation of secondary bile salt species that have biological and physicochemical properties that are distinct from the parent compounds.
Ümran Ay, Martin Leníček, Arno Classen, Steven W. M. Olde Damink, Carsten Bolm, Frank G. Schaap   +5 more
doaj   +1 more source

Isolation and characterization of Faecalibacterium prausnitzii from calves and piglets. [PDF]

, 2014
The goal of our study was to isolate and characterize Faecalibacterium prausnitzii from fecal samples of healthy calves and piglets, in order to develop a novel probiotic for livestock animals.
Bicalho, Rodrigo C, Dias, Juliana M, Foditsch, Carla, Gaeta, Natália, Pereira, Richard VV, Santos, Thiago MA, Teixeira, Andre GV   +6 more
core   +2 more sources

Morphology of bile salts micelles and mixed micelles with lipolysis products, from scattering techniques and atomistic simulations.

Journal of Colloid and Interface Science, 2020
HYPOTHESES Bile salts (BS) are biosurfactants released into the small intestine, which play key and contrasting roles in lipid digestion: they adsorb at interfaces and promote the adsorption of digestive enzymes onto fat droplets, while they also remove ...
Olivia Pabois, Robert M. Ziolek, C. Lorenz, S. Prévost, N. Mahmoudi, M. Skoda, R. Welbourn, M. Valero, R. Harvey, M. Grundy, P. Wilde, I. Grillo, Y. Gerelli, C. A. Dreiss   +13 more
semanticscholar   +1 more source

Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation [PDF]

, 2019
Human ileal bile acid-binding protein (hI-BABP) has a key role in the intracellular transport of bile salts. To explore the role of histidine protonation in the binding process, the pH-dependence of bile salt binding and internal dynamics in hI-BABP was ...
Egyed, Orsolya, Horváth, Gergő, Kardos, József, Kovács, Mihály, Micsonai, András, Tang, Changguo, Toke, Orsolya   +6 more
core   +4 more sources

Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties[S]

Journal of Lipid Research, 2015
Cytotoxic bile acids, such as deoxycholic acid (DCA), are responsible for hepatocyte cell death during intrahepatic cholestasis. The mechanisms responsible for this effect are unclear, and recent studies conflict, pointing to either a modulation of ...
Tânia Sousa, Rui E. Castro, Sandra N. Pinto, Ana Coutinho, Susana D. Lucas, Rui Moreira, Cecília M.P. Rodrigues, Manuel Prieto, Fábio Fernandes   +8 more
doaj   +1 more source

Wormlike reverse micelles in lecithin/bile salt/water mixtures in oil [PDF]

, 2017
Knowing the ability of water and bile salts to promote the reverse wormlike micelle growth in lecithin/water or lecithin/bile salt mixtures in oil, this work was aimed at elucidating the association properties of the three solutes lecithin, water and the
Cautela, Jacopo, Galantini, Luciano, Giustini, Mauro, Palazzo, Gerardo, Pavel, Nicolae Viorel   +4 more
core   +1 more source

Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions

mSphere, 2018
Clostridium difficile is a Gram-positive obligate anaerobe that forms spores in order to survive for long periods in the unfavorable environment outside a host. C. difficile is the leading cause of nosocomial infectious diarrhea worldwide. C.
Travis J. Kochan, Michelle S. Shoshiev, Jessica L. Hastie, Madeline J. Somers, Yael M. Plotnick, Daniela F. Gutierrez-Munoz, Elissa D. Foss, Alyxandria M. Schubert, Ashley D. Smith, Sally K. Zimmerman, Paul E. Carlson, Philip C. Hanna   +11 more
doaj   +1 more source

Preliminary evaluation of probiotic properties of Lactobacillus strains isolated from Sardinian dairy products [PDF]

, 2014
Twenty-three Lactobacillus strains of dairy origin were evaluated for some functional properties relevant to their use as probiotics. A preliminary subtractive screening based on the abilities to inhibit the growth of microbial pathogens and hydrolyze ...
Conti S, Cosentino S, Deiana M, Deplano M, Fadda ME, Melis MP, Pisano MB, Viale S   +7 more
core   +1 more source