Bile Acids and Bile Salts: Ionization and Solubility Properties [PDF]
Hepatology, 1984 The number, position and orientation of nuclear OH substituents profoundly influence the equilibrium solubilities of undissociated bile acids in water. Estimates from several studies range from 5 × 10″8 for lithocholic acid to 1.6 × 10−3 Af for ursocholic acid at 37°C.
Martin C. Carey
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Effect of Digestion on Ursolic Acid Self-Stabilized Water-in-Oil Emulsion: Role of Bile Salts [PDF]
Foods, 2023 Exploring the effect of bile salts on the properties of emulsion carriers containing hydrophobic bioactive compounds is particularly critical to understanding the stability and bioavailability of these hydrophobic bioactive compounds in the digestive ...
Yumeng Yan +3 more
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Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts [PDF]
Journal of Biological Chemistry, 2019 The fish olfactory receptor ORA family is orthologous to the mammalian vomeronasal receptors type 1. It consists of six highly conserved chemosensory receptors expected to be essential for survival and communication.
Xiaojing Cong +9 more
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Role of Bile Acids and Bile Salts in Acute Pancreatitis
Pancreas, 2020 Abstract Acute pancreatitis (AP) is one of the most common gastroenterological disorders leading to hospitalization. It has long been debated whether biliary AP, about 30% to 50% of all cases, is induced by bile acids (BAs) when they reach the pancreas via reflux or via the systemic blood circulation.
Quang Trung Tran +13 more
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Impact of bile salts and a medium chain fatty acid on the physical properties of self-emulsifying drug delivery systems [PDF]
Drug Development and Industrial Pharmacy, 2020 The aim of this study was the evaluation of the influence of bile salts and fatty acids, important components of intestinal fluids, on physical characteristics of self-emulsifying drug delivery systems (SEDDS) such as size, polydispersity (PDI), zeta ...
Noemi Lupo +4 more
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Antimicrobial and healing efficacy of bile salts with insights into cytotoxic activity [PDF]
Scientific ReportsBile salts play crucial roles in lipid digestion and metabolism, with emerging evidence suggesting their involvement in cell signaling, wound healing, and potential antimicrobial activities.
Aisha M. H. Al-Rajhi +6 more
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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling [PDF]
Nature Communications, 2016 AbstractAutotaxin (ATX) generates the lipid mediator lysophosphatidic acid (LPA). ATX-LPA signalling is involved in multiple biological and pathophysiological processes, including vasculogenesis, fibrosis, cholestatic pruritus and tumour progression. ATX has a tripartite active site, combining a hydrophilic groove, a hydrophobic lipid-binding pocket ...
Willem‐Jan Keune +12 more
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Solubility of calcium salts of unconjugated and conjugated natural bile acids.
Journal of Lipid Research, 1992 The approximate solubility products of the calcium salts of ten unconjugated bile acids and several taurine conjugated bile acids were determined. The formation of micelles, gels, and/or precipitates in relation to Ca2+,Na+, and bile salt concentration ...
JJ Gu +4 more
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Bile Salt Composition and Distribution of the D-Cysteinolic Acid Conjugated Bile Salts in Fish
Fisheries science, 1996 Takanobu Goto +5 more
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The Conductance of Conjugated and Unconjugated Bile Acid Salts in Aqueous Solutions. Bile Acids and Steroids. 80. [PDF]
Acta Chemica Scandinavica, 1960 A. Norman +4 more
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