Results 21 to 30 of about 27,297 (261)

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Method for removal of surface-active impurities and calcium from conjugated bile salt preparations: comparison with silicic acid chromatography.

Journal of Lipid Research, 1995
Some commercial preparations of common natural conjugated bile salts contain impurities (e.g., amines, lipids, and calcium) that are likely to affect their physicochemical properties. A method was developed for purifying commercial preparations of sodium
S. Del Vecchio, J.D. Ostrow, P. Mukerjee, H.T. Ton-Nu, C.D. Schteingart, A.F. Hofmann, C. Cerrè, A. Roda   +7 more
doaj   +1 more source

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

npj Biofilms and Microbiomes, 2022
The Clostridioides difficile pathogen is responsible for nosocomial infections. Germination is an essential step for the establishment of C. difficile infection (CDI) because toxins that are secreted by vegetative cells are responsible for the symptoms ...
Andrea Martinez Aguirre, Adegoke Oyeleye Adegbite, Joseph A. Sorg   +2 more
doaj   +1 more source

A phylogenetic survey of biliary lipids in vertebrates1,

Journal of Lipid Research, 2005
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta, Fang Xu, Lee R. Hagey, Gerard P. van Berge-Henegouwen, Karel J. van Erpecum, Jos F. Brouwers, Jonathan C. Cohen, Molly Bierman, Helen H. Hobbs, Joseph H. Steinbach, Alan F. Hofmann   +10 more
doaj   +1 more source

A high-throughput LC-MS/MS method for the measurement of the bile acid/salt content in microbiome-derived sample sets

MethodsX, 2020
Due to the physicochemical properties of bile acids/salts (i.e., hydrophobic and ionizable), the application of reverse-phase liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based methods are ideally suited for the measurement of these ...
Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Jennifer M. Auchtung, Anthony M. Haag   +4 more
doaj   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

Angewandte Chemie, EarlyView.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan, Andrew J. Tague, Ashna A. Kumar, Marie Ranson, Christopher J. T. Hyland, Shane R. Ellis   +5 more
wiley   +2 more sources

Bile salt evolution

Journal of Lipid Research, 1967
Viewed against the background of known or supposed biosynthetic pathways for cholic and chenodeoxycholic acids in man and laboratory animals, the chemical nature of bile salts in more primitive animals clearly indicates that evolution from C27, 5α ...
G.A.D. Haslewood
doaj   +1 more source

Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts [PDF]

Journal of Biological Chemistry, 2019
The fish olfactory receptor ORA family is orthologous to the mammalian vomeronasal receptors type 1. It consists of six highly conserved chemosensory receptors expected to be essential for survival and communication. We deorphanized the zebrafish ORA family in a heterologous cell system. The six receptors responded specifically to lithocholic acid (LCA)
Xiaojing Cong, Qian Zheng, Wenwen Ren, Jean-Baptiste Chéron, Sébastien Fiorucci, Tieqiao Wen, Chunbo Zhang, Hongmeng Yu, Jérôme Golebiowski, Yiqun Yu   +9 more
openaire   +3 more sources

The regulatory mechanism of acidic tea polysaccharides from Wuyi rock tea on bile acids in type 2 diabetic rats

Shipin yu jixie
ObjectiveThis study aimed to investigate the effects of an acidic tea polysaccharide extracted from Wuyi Rock tea "yellow slice" on bile acids in hyperglycaemic rats.MethodsIn vitro experiments simulating artificial gastric and intestinal fluids were ...
WU Zhong, YANG Jiangfan
doaj   +1 more source

Comparison of Biochemical Characteristics of Lactobacilli Isolates from Food and Bovine Rumen Sources under Low pH and Bile Salt Stress Conditions

Chemical Engineering Transactions, 2017
In this study, two lactobacilli isolates, from dairy food and bovine rumen, were used to investigate the differences in their biochemical characteristics when exposed to low pH and bile salt stress conditions.
N.M. Jose, C.R. Bunt, M.A. Hussain
doaj   +1 more source