Results 41 to 50 of about 63,714 (388)

Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat.

Journal of Lipid Research, 1989
Hepatic bile acid synthesis is thought to be under negative feedback control by bile salts in the enterohepatic circulation, acting at the level of cholesterol 7 alpha-hydroxylase (C7 alpha H), the initial and rate-limiting step in the bile acid ...
D M Heuman, P B Hylemon, Z R Vlahcevic
doaj   +1 more source

Method for removal of surface-active impurities and calcium from conjugated bile salt preparations: comparison with silicic acid chromatography.

Journal of Lipid Research, 1995
Some commercial preparations of common natural conjugated bile salts contain impurities (e.g., amines, lipids, and calcium) that are likely to affect their physicochemical properties. A method was developed for purifying commercial preparations of sodium
S. Del Vecchio, J.D. Ostrow, P. Mukerjee, H.T. Ton-Nu, C.D. Schteingart, A.F. Hofmann, C. Cerrè, A. Roda   +7 more
doaj   +1 more source

Bile acids: Lipase-catalyzed synthesis of new hyodeoxycholic acid derivatives [PDF]

, 2018
In this work we present an efficient, environmentally friendly approach to the synthesis of a series of hyodeoxycholic acid derivatives applying Biocatalysis.
Baldessari, Alicia, Chanquia, Santiago Nahuel, Garcia Liñares, Guadalupe Eugenia, Ripani, Erika Aldana   +3 more
core   +1 more source

A phylogenetic survey of biliary lipids in vertebrates1,

Journal of Lipid Research, 2005
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta, Fang Xu, Lee R. Hagey, Gerard P. van Berge-Henegouwen, Karel J. van Erpecum, Jos F. Brouwers, Jonathan C. Cohen, Molly Bierman, Helen H. Hobbs, Joseph H. Steinbach, Alan F. Hofmann   +10 more
doaj   +1 more source

A high-throughput LC-MS/MS method for the measurement of the bile acid/salt content in microbiome-derived sample sets

MethodsX, 2020
Due to the physicochemical properties of bile acids/salts (i.e., hydrophobic and ionizable), the application of reverse-phase liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based methods are ideally suited for the measurement of these ...
Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Jennifer M. Auchtung, Anthony M. Haag   +4 more
doaj   +1 more source

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

npj Biofilms and Microbiomes, 2022
The Clostridioides difficile pathogen is responsible for nosocomial infections. Germination is an essential step for the establishment of C. difficile infection (CDI) because toxins that are secreted by vegetative cells are responsible for the symptoms ...
Andrea Martinez Aguirre, Adegoke Oyeleye Adegbite, Joseph A. Sorg   +2 more
doaj   +1 more source

Piacentinu Ennese PDO cheese as reservoir of promising probiotic bacteria [PDF]

, 2019
Piacentinu Ennese is a protected designation of origin (PDO) cheese produced in the surrounding area of Enna (Sicily, Italy), using raw ewe’s milk without the addition of any starter cultures.
Caggia, Cinzia, De Angelis, Maria, Pino, Alessandra, Randazzo, Cinzia Lucia, Russo, Nunziatina, Sferrazzo, Giuseppe, Van Hoorde, Koenraad   +6 more
core   +2 more sources

Bile salt evolution

Journal of Lipid Research, 1967
Viewed against the background of known or supposed biosynthetic pathways for cholic and chenodeoxycholic acids in man and laboratory animals, the chemical nature of bile salts in more primitive animals clearly indicates that evolution from C27, 5α ...
G.A.D. Haslewood
doaj   +1 more source

Comparison of Cholesterol Lowering Diets: Apple, Casein Cytochrom P450 protein and Cholesterol 7α Hydroxylase Activities in Hamsters [PDF]

, 2010
Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement.
Rakesh Sharma, Rakesh K. Tandon
core   +2 more sources

Human and rat bile acid–CoA:amino acid N -acyltransferase are liver-specific peroxisomal enzymes: Implications for intracellular bile salt transport [PDF]

Hepatology, 2007
Bile acid–coenzyme A:amino acid N -acyltransferase (BAAT) is the sole enzyme responsible for conjugation of primary and secondary bile acids to taurine and ...
Pellicoro, Antonella, van den Heuvel, Fiona A. J., Geuken, Mariska, Moshage, Han, Jansen, Peter L. M., Faber, Klaas Nico   +5 more
openaire   +2 more sources