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High-resolution metabolomic analysis of stool reveals expanded biomarkers of <i>C. difficile</i> colitis and insights into pathophysiology. [PDF]

open access: yesMicrobiol Spectr
Mehta N   +9 more
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Bile salt related secretion of acid phosphatase in rat bile

Canadian Journal of Physiology and Pharmacology, 1986
The biliary excretion of bile salts, lysosomal acid phosphatase, and total proteins were studied in rats under different experimental conditions: (i) during bile salt loss through a bile fistula and (ii) after loading with exogenous sodium taurocholate. The experimental models were suitable to demonstrate that variations in the excretion of bile salts
R A, Marinelli   +2 more
openaire   +2 more sources

Cholesterol, bile acid and bile salt adsorption to bran in vitro

Pharmacological Research Communications, 1981
Summary The in vitro adsorption of cholesterol (C) (0.6–1.1mM), bile acids (BA) and bile salts (BS) (5–10mM) on to bran and Amberlite XAD-2 (0.5 g) was studied. After the mixtures were shaken, three phases were obtained: phase 1 (the supernatant containing no bound lipids) phase 2 (bran and Amberlite were washed with buffer in order to obtain weakly ...
G, Salvioli   +3 more
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A Comparative Study of the Choleretic Effect of Bile Salts and Oleic Acid and Bile Salts

Annals of Internal Medicine, 1933
Excerpt For the past year we have employed a mixture of oleic acid and bile salts for the treatment of patients suffering from various forms of gall-bladder disease.
REUBEN FINKELSTEIN, EMANUEL W. LIPSCHUTZ
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Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat

Digestive Diseases and Sciences, 1994
Taurohyodeoxycholic acid is a natural 6 alpha-hydroxylated bile acid with an apparent hydrophilicity intermediate between those of tauroursodeoxycholic and taurocholic acids. We investigated in the rat the hepatobiliary metabolism, choleretic properties, and biliary maximum secretory rate (SRmax) of taurohyodeoxycholic in comparison with these two bile
Mario Angelico   +5 more
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Bile Acids and Bile Salts: Ionization and Solubility Properties

Hepatology, 1984
The number, position and orientation of nuclear OH substituents profoundly influence the equilibrium solubilities of undissociated bile acids in water. Estimates from several studies range from 5 × 10″8 for lithocholic acid to 1.6 × 10−3 Af for ursocholic acid at 37°C.
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Effects of acid and bile salts on the rabbit esophageal mucosa

Digestive Diseases and Sciences, 1981
We used the rabbit esophagus as a model to study clinically significant variables which may be important in the pathophysiology of reflux esophagitis in man.* Increased permeability to hydrogen ion, as indicated by a net acid flux (NAF) out of the lumen, was our index of injury.
J W, Harmon   +2 more
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