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Sodium salts of bile acids in aqueous micellar solutions

2007
Aqueous micellar solutions of deoxycholate (DC), glycodeoxycholate (GDC), and taurodeoxycholate (TDC) were studied to find the predominant species and their formation constants.
BOTTARI, Emilio Giovanni   +1 more
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Bile salt hydrolase acyltransferase activity expands bile acid diversity

Nature
Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome because of their antimicrobial properties1-4. Here we identify the enzyme responsible for a mechanism of BA metabolism by the gut microbiota involving amino acid conjugation to the acyl-site of BAs, thus ...
Douglas V. Guzior   +14 more
openaire   +2 more sources

Micellar behaviour in solutions of bile-acid salts

Kolloid-Zeitschrift & Zeitschrift für Polymere, 1971
Micellar behaviour in solutions of bile-acid salts : II.
  +5 more sources

Bile salt tolerance of Lactococcus lactis is enhanced by expression of bile salt hydrolase thereby producing less bile acid in the cells

Biotechnology Letters, 2015
Changes of bile salt tolerance, morphology and amount of bile acid within cells were studied to evaluate the exact effects of bile salt hydrolase (BSH) on bile salt tolerance of microorganism.The effect of BSHs on the bile salt tolerance of Lactococcus lactis was examined by expressing two BSHs (BSH1 and BSH2). Growth of L.
Jie, Bi   +3 more
openaire   +2 more sources

The ionic behavior of fatty acids solubilized by bile salts

Journal of Colloid and Interface Science, 1970
Abstract The influence of different bile salts on the ionic behavior of oleic acid, in the presence and absence of salt, has been investigated symmetrically by a titration study. The effect of ionic strength, degree of ionization, and the ratio oleic acid bile salt, on the composition and size of the mixed micelles in these systems has been ...
openaire   +2 more sources

Polycationic salts as bile acid sequestering agents

Progress in Polymer Science, 1999
Abstract A review of bile acid chemistry is included in this paper. The structures, chemistry, physiology and metabolism of the bile acids and their effects on the human body are discussed. Additionally, the precursor of bile acids are examined at length as are current treatments for diseases arising from high levels of cholesterol or the ...
P. Zarras, O. Vogl
openaire   +1 more source

Bile and pancreatic secretion in chickens: the effects of bile salts, feeding and acid

Comparative Biochemistry and Physiology Part A: Physiology, 1978
Abstract 1. 1. Bile production decreased after bile diversion, but increased when bile was returned to the duodenum, and during i.v. infusion of chenodeoxycholic and of taurocholic acid. In chickens, unlike rabbits, rats and guinea pigs, only a small fraction of bile flow was apparently independent of bile salt secretion. 2. 2.
Ivan W Caple, C.G Halpin, Trevor Heath
openaire   +1 more source

Group separation of bile acids and salts by silicic acid column chromatography

Analytical Biochemistry, 1978
Abstract Group separations of unconjugated and conjugated bile acids and salts were performed using mixtures of conventional solvents by chromatography on columns of silicic acid. The results suggest that this method is useful for group separations of mono-, di-, and trihydroxycholan-24-oic acids and their conjugates with good recoveries. This method
openaire   +2 more sources

Inhibition of human milk bile-salt-dependent lipase by boronic acids. Implication to the bile salts activator effect

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1989
The bile-salt-dependent lipase from human milk, which catalyzes the hydrolysis of the water-soluble substrate 4-nitrophenyl acetate and the water-insoluble substrate tributyrin, is competitively inhibited by phenyl boronic acid. This inhibitor does not interfere with the interaction of lipase either with the siliconized glass beads/water interface or ...
N, Abouakil, D, Lombardo
openaire   +2 more sources

Comparison of the Binding of Various Bile Acids and Bile Salts in Vitro by Several Types of Fiber

The Journal of Nutrition, 1976
The binding in vitro of the sodium salts of cholic acid, chenodeoxycholic acid, deoxycholic acid, taurocholic acid, taurochenodeoxycholic acid, taurodeoxycholic acid, glycocholic acid, glycochenodeoxycholic acid, and glycodeoxycholic acid by alfalfa, bran, cellulose, lignin, and cholestyramine was measured.
J A, Story, D, Kritchevsky
openaire   +2 more sources

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