The Causal Role of Bile Acids in Cancers of the Digestive System [PDF]
BiomedicinesBile acids are widely distributed in the human gastrointestinal tract. A literature review indicates that bile acids may have a role in initiating cancers in every organ of the digestive system.
Carol Bernstein, Harris Bernstein
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Investigation of bile salt hydrolase activity in human gut bacteria reveals production of conjugated secondary bile acids [PDF]
Nature CommunicationsThrough biochemical transformation of host-derived bile acids, gut bacteria mediate host-microbe crosstalk and function at the interface of nutrition and host metabolic regulation.
Lauren N. Lucas +10 more
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Efficacy of a Tibia Counter Rotator System for the Treatment of Internal Tibial Torsion in Children
Children, 2022 Internal tibial torsion is more common in the Asian population than in Western populations. Generally, surgery should be considered for the treatment of severe internal tibial torsion. As an alternative approach, the usefulness of a tibia counter rotator
Sungmi Kim +4 more
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Bile acids as inflammatory mediators and modulators of intestinal permeability
Frontiers in Immunology, 2022 Bile acids are critical for the digestion and absorption of lipids and fat-soluble vitamins; however, evidence continues to emerge supporting additional roles for bile acids as signaling molecules. After they are synthesized from cholesterol in the liver,
Nathan Calzadilla +9 more
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Bile acid patterns in commercially available oxgall powders used for the evaluation of the bile tolerance ability of potential probiotics. [PDF]
PLoS ONE, 2018 This study aimed to analyze the bile acid patterns in commercially available oxgall powders used for evaluation of the bile tolerance ability of probiotic bacteria.
Peng-Li Hu +3 more
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Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
, 2020 In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco +4 more
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A Recent Ten-Year Perspective: Bile Acid Metabolism and Signaling
Molecules, 2022 Bile acids are important physiological agents required for the absorption, distribution, metabolism, and excretion of nutrients. In addition, bile acids act as sensors of intestinal contents, which are determined by the change in the spectrum of bile ...
Yulia Shulpekova +13 more
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Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). [PDF]
PLoS ONE, 2016 Besides their role in intestinal resorption of lipids, bile acids are regarded as endocrine and metabolic signaling molecules. The detailed profile of bile acid species in peripheral blood after an oral lipid tolerance test (OLTT) is unknown.We ...
Andreas Schmid +4 more
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Bile Acids: Physiological Activity and Perspectives of Using in Clinical and Laboratory Diagnostics
Molecules, 2022 Bile acids play a significant role in the digestion of nutrients. In addition, bile acids perform a signaling function through their blood-circulating fraction. They regulate the activity of nuclear and membrane receptors, located in many tissues.
Yaroslav Shansky, Julia Bespyatykh
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Journal of Lipid Research, 2009 In liver and intestine, transporters play a critical role in maintaining the enterohepatic circulation and bile acid homeostasis. Over the past two decades, there has been significant progress toward identifying the individual membrane transporters and unraveling their complex regulation.
Paul A. Dawson, Tian Lan, Anuradha Rao
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