Bile acids as inflammatory mediators and modulators of intestinal permeability
Frontiers in Immunology, 2022 Bile acids are critical for the digestion and absorption of lipids and fat-soluble vitamins; however, evidence continues to emerge supporting additional roles for bile acids as signaling molecules. After they are synthesized from cholesterol in the liver,
Nathan Calzadilla +9 more
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Biosynthesis and biotransformation of bile acids [PDF]
Hospital Pharmacology, 2017 Bile acids are steroidal compounds, which contain 24 carbon atoms. They can be classified into two major groups: primary and secondary. The most abundant bile acids: The primary bile acids include cholic acid and chenodeoxycholic acid, while the major ...
Šarenac Tanja M., Mikov Momir M.
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The Causal Role of Bile Acids in Cancers of the Digestive System [PDF]
BiomedicinesBile acids are widely distributed in the human gastrointestinal tract. A literature review indicates that bile acids may have a role in initiating cancers in every organ of the digestive system.
Carol Bernstein, Harris Bernstein
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Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3. [PDF]
PLoS ONE, 2017 Bile acids, the metabolites of cholesterol, are signaling molecules that play critical role in many physiological functions. They undergo enterohepatic circulation through various transporters expressed in intestine and liver.
Takahiro Suga +5 more
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Bile acids and their receptors.
Molecular Aspects of Medicine, 2017 International audiencePrimary bile acids are synthetized from cholesterol within the liver and then transformed by the bacteria in the intestine to secondary bile acids.
Baptissart, Marine +6 more
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Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids
Acta Pharmaceutica Sinica B, 2015 The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids also act as signaling molecules to regulate glucose homeostasis, lipid metabolism and energy ...
Courtney B. Ferrebee, Paul A. Dawson
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Investigation of bile salt hydrolase activity in human gut bacteria reveals production of conjugated secondary bile acids [PDF]
Nature CommunicationsThrough biochemical transformation of host-derived bile acids, gut bacteria mediate host-microbe crosstalk and function at the interface of nutrition and host metabolic regulation.
Lauren N. Lucas +10 more
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Efficacy of a Tibia Counter Rotator System for the Treatment of Internal Tibial Torsion in Children
Children, 2022 Internal tibial torsion is more common in the Asian population than in Western populations. Generally, surgery should be considered for the treatment of severe internal tibial torsion. As an alternative approach, the usefulness of a tibia counter rotator
Sungmi Kim +4 more
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Bile acid patterns in commercially available oxgall powders used for the evaluation of the bile tolerance ability of potential probiotics. [PDF]
PLoS ONE, 2018 This study aimed to analyze the bile acid patterns in commercially available oxgall powders used for evaluation of the bile tolerance ability of probiotic bacteria.
Peng-Li Hu +3 more
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Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). [PDF]
PLoS ONE, 2016 Besides their role in intestinal resorption of lipids, bile acids are regarded as endocrine and metabolic signaling molecules. The detailed profile of bile acid species in peripheral blood after an oral lipid tolerance test (OLTT) is unknown.We ...
Andreas Schmid +4 more
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