Cholestasis impairs gut microbiota development and bile salt hydrolase activity in preterm neonates
Gut Microbes, 2023 Cholestasis refers to impaired bile flow from the liver to the intestine. In neonates, cholestasis causes poor growth and may progress to liver failure and death.
Lauren E. Lynch +7 more
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Bile salts of vertebrates: structural variation and possible evolutionary significance[S]
Journal of Lipid Research, 2010 Biliary bile salt composition of 677 vertebrate species (103 fish, 130 reptiles, 271 birds, 173 mammals) was determined. Bile salts were of three types: C27 bile alcohols, C27 bile acids, or C24 bile acids, with default hydroxylation at C-3 and C-7.
Alan F. Hofmann +2 more
doaj +1 more source
Bile Acid Detection Techniques and Bile Acid-Related Diseases
Frontiers in Physiology, 2022 Bile acid is a derivative of cholinergic acid (steroidal parent nucleus) that plays an important role in digestion, absorption, and metabolism. In recent years, bile acids have been identified as signaling molecules that regulate self-metabolism, lipid metabolism, energy balance, and glucose metabolism.
Xiang Zhao +5 more
openaire +3 more sources
Bile Acids Conjugation in Human Bile Is Not Random: New Insights from 1H-NMR Spectroscopy at 800 MHz [PDF]
, 2009 Bile acids constitute a group of structurally closely related molecules and represent the most abundant constituents of human bile. Investigations of bile acids have garnered increased interest owing to their recently discovered additional biological ...
Cooper, Amanda +4 more
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Hepatic bile acid uptake: effect of conjugation, hydroxyl and keto groups, and albumin binding
Journal of Lipid Research, 1982 Hepatic extraction of trihydroxy (free, glyco- and tauro-conjugated) dihydroxy, and monohydroxy bile acids has been evaluated in single pass liver perfusion experiments in rats.
R Aldini +5 more
doaj +1 more source
Annals of Hepatology, 2017 The primary bile acids (BAs) are synthetized from colesterol in the liver, conjugated to glycine or taurine to increase their solubility, secreted into bile, concentrated in the gallbladder during fasting, and expelled in the intestine in response to dietary fat, as well as bio-transformed in the colon to the secondary BAs by the gut microbiota ...
Agostino Di Ciaula +6 more
openaire +4 more sources
Experimental isovalthinuria. III. Induction by bile acids, and hypocholesterolemic agents [PDF]
, 1963 Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in ...
Ubuka, Toshihiko
core +1 more source
Journal of Lipid Research, 1994 Recently we showed that supplemental dietary calcium stimulates the intestinal formation of insoluble calcium phosphate and decreases the ratio of dihydroxy to trihydroxy bile acids in human duodenal bile. Because previous in vitro studies indicated that
M J Govers +3 more
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Bile acids. LXVII. The major bile acids of Varanus monitor
Journal of Lipid Research, 1982 The major bile acids of gall bladder bile of Varanus monitor have been separated by thin-layer chromatography and shown to be derivatives of taurine.
S S Ali, E Stephenson, W H Elliott
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Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]
, 1999 In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Hammer, C. +7 more
core +1 more source