The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A. +8 more
core +1 more source
Pancreas divisum. Correlation between anatomical abnormalities and bile precipitation in the gallbladder in seven patients [PDF]
Pancreas divisum is a genetic defect associated with recurrent acute pancreatitis due to insufficient drainage of the accessory pancreatic duct. Seven young patients diagnosed with pancreatic divisum and thickening of the gallbladder bile as shown on ...
AL MANSOUR, Monir +12 more
core +1 more source
Relation of Gallbladder Motility to Viscosity and Composition of Gallbladder Bile in Patients with Cholesterol Gallstones [PDF]
Background/Aims: Increased viscosity and supersaturation of cholesterol in gallbladder bile, as well as an impaired motility of the gallbladder, are considered to be important factors in the pathogenesis of cholesterol gallstones.
Althaus, Rupert +9 more
core +1 more source
A positive SeHCAT test results in fewer subsequent investigations in patients with chronic diarrhoea. [PDF]
Chronic diarrhoea is a common condition, resulting from a number of different disorders. Bile acid diarrhoea, occurring in about a third of these patients, is often undiagnosed.
Appleby, RN +3 more
core +1 more source
Expression, purification, crystallization and preliminary X-ray diffraction analysis of conjugated bile salt hydrolase from Bifidobacterium longum [PDF]
Conjugated bile salt hydrolase (BSH) catalyses the hydrolysis of the amide bond that conjugates bile acids to glycine and to taurine. The BSH enzyme from Bifidobacterium longum was overexpressed in Escherichia coli BL21(DE3), purified and crystallized ...
Kumar, R S +5 more
core +2 more sources
Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation [PDF]
Human ileal bile acid-binding protein (hI-BABP) has a key role in the intracellular transport of bile salts. To explore the role of histidine protonation in the binding process, the pH-dependence of bile salt binding and internal dynamics in hI-BABP was ...
Egyed, Orsolya +6 more
core +4 more sources
Relation of gallbladder function and Helicobacter pylori infection to gastric mucosa inflammation in patients with symptomatic cholecystolithiasis [PDF]
Background. Inflammatory alterations of the gastric mucosa are commonly caused by Helicobacter pylori (Hp) infection in patients with symptomatic gallstone disease.
Abdel-Wahab M +38 more
core +1 more source
Effect of Intraduodenal Bile and Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Vasoactive Intestinal Polypeptide and Somatostatin in Man [PDF]
Intraduodenal (i.d.) application of bile or Na-taurodeoxycholate (TDC) dose dependently enhances basal exocrine pancreatic secretion. The hydrokinetic effect is mediated at least in part by secretin.
Fiedler, Fritz +3 more
core +1 more source
Deficiency of Capicua disrupts bile acid homeostasis [PDF]
Capicua (CIC) has been implicated in pathogenesis of spinocerebellar ataxia type 1 and cancer in mammals; however, the in vivo physiological functions of CIC remain largely unknown.
Choi, N +12 more
core +2 more sources
Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell +59 more
core +1 more source

