Results 181 to 190 of about 196,612 (310)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Laser lithotripsy for refractory stones in the cystic duct and common bile duct. [PDF]

Endoscopy
Miwa H, Ishino Y, Endo K, Oishi R, Suzuki Y, Tsuchiya H, Maeda S.   +6 more
europepmc   +1 more source

Double Common Bile Duct

Internal Medicine, 2019
Endoh, Bunji, Esaka, Naoki, Ota, Yoshiyuki, Katsushima, Shinji   +3 more
openaire   +3 more sources

Mind the gap! Extraluminal percutaneous-endoscopic rendezvous with a self-expanding metal stent for restoring continuity in major bile duct injury: A case series [PDF]

, 2019
Bernon, Marc, Burmeister, Sean, Jonas, Eduard, Kloppers, Christo, Lindemann, Jessica   +4 more
core   +2 more sources

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source

Mesenchymal stromal cell administration promotes macrophage-mediated bile duct regeneration. [PDF]

Regen Ther
Igarashi T, Kimura N, Abe H, Yoshida T, Watanabe Y, Kamimura H, Sakamaki A, Yokoo T, Kamimura K, Tsuchiya A, Terai S.   +10 more
europepmc   +1 more source

Intrahepatic bile duct strictures in a liver allograft recipient mimicking recurrent primary sclerosing cholangitis - Follow-up of a case report [PDF]

, 1991
Demetris, AJ, Gordon, R, Hartman, GG, Lerut, J, Starzl, TE   +4 more
core   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography for Bile Duct Stones-Avoiding the Avoidable. [PDF]

Biomedicines
Chiriac S, Sfarti C, Minea H, Zenovia S, Girleanu I, Huiban L, Muzica C, Rotaru A, Stafie R, Nastasa R, Stratina E, Ciuntu BM, Avram R, Trifan A.   +13 more
europepmc   +1 more source

Intratumoral bacteria engineered for tumor therapy

Interdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang, Zelin Chen, Zeyu Yao, Sishi Luo, Cheng Luo, Rui Yang, Hao Fu, Songyin Huang   +7 more
wiley   +1 more source