Results 271 to 280 of about 268,242 (398)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Bile Duct Stenosis in a Free-Ranging Juvenile American Black Bear (<i>Ursus americanus</i>). [PDF]

Animals (Basel)
Jurgens T, Nelson F, Sheley W, Johnson A, Swanepoel L, Wyckoff S, Sheldon JD.   +6 more
europepmc   +1 more source

Highly Reproducible, Vendor‐Agnostic, Motion‐Insensitive Liver PDFF Mapping at 0.55T, 1.5T, and 3T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and validate a vendor‐agnostic, motion‐insensitive proton‐density fat‐fraction (PDFF) quantification method. Methods Flip‐angle‐modulated (FAM) 2D chemical‐shift‐encoded (CSE) MRI for PDFF quantification was implemented in both the vendor‐agnostic platform Pulseq (“Pulseq‐FAM”) and one vendor‐specific platform (“GE‐specific ...
Jiayi Tang, Daiki Tamada, Jon‐Fredrik Nielsen, Jitka Starekova, Julius F. Heidenreich, Felix Schön, Alexandra A. Anagnostopoulos, Amirhossein Roshanshad, Lu Mao, Shohei Fujita, Pengcheng Xu, Christopher Keen, Imam Ahmed Shaik, Eugene Milshteyn, Seonghwan Yee, Andrew J. Ellison, David Rutkowski, Jeff Kammerman, Jean H. Brittain, Xiaodong Zhong, William A. Grissom, Maxim Zaitsev, Aaron L. Carrel, Yogesh Rathi, Yun Jiang, Berkin Bilgic, Scott B. Reeder, Diego Hernando   +27 more
wiley   +1 more source

Endoscopic treatment of choledochal cyst injury complicated by pneumothorax and pneumomediastinum after endoscopic retrograde cholangiopancreatography in a pregnant woman. [PDF]

Prz Gastroenterol
Ibekenov OT, Baimakhanov BB, Abdirashev YB, Abdykadyrov MK, Berkinbay A.   +4 more
europepmc   +1 more source

Therapeutic potential of tetrahydroxylated bile acids in reducing liver injury: Insights from the Zfyve19−/− mouse model

Pediatric Investigation, EarlyView.
THBA (3α,6α,7α,12α‐Tetrahydroxy‐10β,13β‐pentanoic acid) administration can alleviate cholestatic liver injury, hepatocellular necrosis, inflammatory response, bile duct hyperplasia, and portal fibrosis in the Zfyve19−/− mouse model. This evaluation encompasses various parameters, including serum biochemistry, liver histology, immunostaining, and ...
Li Wang, Yue Yu, Jiayan Feng, Yanan Zhang, Renxue Wang, Huiyu She, Teng Liu, Victor Ling, Jianshe Wang   +8 more
wiley   +1 more source

Machine learning-based prediction of recurrent extrahepatic bile duct stones after common bile duct exploration: a comparative study of models and SHAP-driven interpretability analysis. [PDF]

Front Med (Lausanne)
Cao Y, Hu X, Guo J, Fang T.
europepmc   +1 more source

Machine Learning‐Based Risk‐Adjusted CUSUM Control Chart for Monitoring Readmission Rate Following PTBD Catheter Placement

Quality and Reliability Engineering International, EarlyView.
ABSTRACT Percutaneous transhepatic biliary drainage (PTBD) catheter placement is known to have a high readmission rate. This work focuses on monitoring the change in readmission rate after a new clinical paradigm for post‐procedural care is implemented for the PTBD procedures.
Muhammed Aljifri, Yanjun Qian, Kunal Patel   +2 more
wiley   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Role of HLA Class II-specific alloreactive T cells in biliary epithelium injury associated with liver transplant rejection [PDF]

, 1988
Demetris, AJ, Duquesnoy, R, Fung, J, Markus, B, Saidman, S, Starzl, T, Zeevi, A   +6 more
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