Results 1 to 10 of about 16,016 (250)
Gut Microbes, 2023 Cholestasis is a condition characterized by the abnormal production or excretion of bile, and it can be induced by a variety of causes, the factors of which are extremely complex.
Leilei Yu, Shunhe Wang, Arjan Narbad
exaly +3 more sources
Cholestasis: human disease and experimental animal models
Annals of Hepatology, 2003 Cholestasis may result from a failure in bile secretion in hepatocytes or ductular cells, or from a blockade to the free bile flow. Human cholestasis may be induced by many drugs, being antibiotics the more common.
Emilio Alberto Rodríguez-Garay, MD, PhD
exaly +3 more sources
Linking abnormal bile acid homeostasis and endocrine component of intrahepatic cholestasis of pregnancy [PDF]
Nature Reviews Gastroenterology and Hepatology, 2012 exaly +2 more sources
Biomarkers of Cholestasis [PDF]
Biomarkers in Medicine, 2021 Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Pieters, Alanah +5 more
openaire +4 more sources
JHEP Reports, 2023 Background & Aims: Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare liver disease caused by biallelic variations in ABCB4. Data reporting on the impact of genotype and of response to ursodeoxycholic acid (UDCA) therapy on long ...
Emmanuel Gonzales +18 more
doaj +1 more source
Effect of transient obstructive cholestasis on liver histology: a cross-sectional study
São Paulo Medical Journal, 2021 BACKGROUND: The role of transient obstructive cholestasis on liver histology remains undetermined. OBJECTIVE: To investigate whether transient cholestasis impairs liver histology.
Thalita Mendes Mitsunaga +8 more
doaj +1 more source
CHRONIC CHOLESTASIS IN INFANCY [PDF]
Romanian Journal of Pediatrics, 2009 This article focuses on the few disorders that produce chronic cholestasis in infants. The author presents: definition and pathophysiology of cholestasis; the consequences of cholestasis; an approach to diagnosis of cholestasis in infancy and childhood;
Daniela Patrichi
doaj +1 more source
Frontiers in Pediatrics, 2023 AimThis study aimed to summarize and show the characteristics and evolutionary process of neonatal cholestasis caused by McCune–Albright syndrome (MAS), as neonatal cholestasis may be the initial manifestation of MAS before other classic clinical ...
Weiyuan Fang +3 more
doaj +1 more source
AJOG Global Reports, 2021 BACKGROUND: Gestational diabetes and obstetrical cholestasis are common clinical conditions seen in clinical practice. There is evidence suggesting a coexisting relationship that could have a potential clinical implication related to stillbirth outcomes.
Manoj Mohan, MRCOG +3 more
doaj +1 more source
Hypercortisolism in patients with cholestasis is associated with disease severity
BMC Gastroenterology, 2021 Background Cholestasis might lead to an impairment of adrenal function as suggested by in vitro and in vivo data as well as by clinical findings. Bile acid and adrenal steroid metabolism not only share the receptors farnesoid X receptor (FXR) and the G ...
Verena Theiler-Schwetz +6 more
doaj +1 more source