An Interactive Automation for Human Biliary Tree Diagnosis Using Computer Vision [PDF]
The biliary tree is a network of tubes that connects the liver to the gallbladder, an organ right beneath it. The bile duct is the major tube in the biliary tree. The dilatation of a bile duct is a key indicator for more major problems in the human body, such as stones and tumors, which are frequently caused by the pancreas or the papilla of vater. The
arxiv
Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico+6 more
core +1 more source
Application of endoscopic ultrasound interventional therapy in biliary and pancreatic diseases [PDF]
Endoscopic ultrasound (EUS) has been greatly developed in the diagnosis of digestive diseases. In recent years, with the continuous innovation of endoscopic technology and accessories, important breakthroughs have been made in endoscopic ultrasound ...
HOU Senlin, YU Tingting, LIU Pengxiang, ZHANG Lichao
doaj +1 more source
Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]
Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv
Intrahepatic cholangiocarcinoma: review and update [PDF]
Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies that could develop at any level from the biliary tree. CCA is currently classified into intrahepatic (iCCA), perihilar and distal on the basis of its anatomical location.
Alvaro, Domenico+7 more
core +1 more source
REMEDI: REinforcement learning-driven adaptive MEtabolism modeling of primary sclerosing cholangitis DIsease progression [PDF]
Primary sclerosing cholangitis (PSC) is a rare disease wherein altered bile acid metabolism contributes to sustained liver injury. This paper introduces REMEDI, a framework that captures bile acid dynamics and the body's adaptive response during PSC progression that can assist in exploring treatments.
arxiv
Liver resections: complications and survival outcome [PDF]
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core +1 more source
Recent update of therapeutic application of peroral cholangioscopy
Despite advancements in endoscopic retrograde cholangiopancreatography (ERCP), direct endoscopic visualization of the biliary tree by cholangioscopy is required to improve the diagnosis and treatment of the underlying disease.
Yun Nah Lee
doaj +1 more source
The diagnostic and prognostic value of UBE2T in intrahepatic cholangiocarcinoma [PDF]
Background Ubiquitin-conjugating enzyme E2T (UBE2T) is overexpressed in several types of malignancies. However, little is known about its diagnostic significance in intrahepatic cholangiocarcinoma (ICC) and other bile duct diseases or its prognostic ...
Hua Yu+8 more
doaj +2 more sources
Peribiliary glands are key in regeneration of the human biliary epithelium after severe bile duct injury [PDF]
Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of luminal biliary epithelium has been proposed to activate PBG, resulting in cell proliferation ...
Carpino, Guido+15 more
core +3 more sources